Carrara Mathieu, Gaillard Anne-Laure, Brion Alice, Duvernois-Berthet Evelyne, Giovannangeli Carine, Concordet Jean-Paul & Pézeron Guillaume, February 2025 — Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish. Double strand breaks (DSBs) are the most deleterious DNA lesions as they frequently result in mutations when repaired by… Scientific Reports vol. 15, n° 1, p. 4886
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-025-88564-6
Chamas Lamis, Seugnet Isabelle, Tanvé Odessa, Enderlin Valérie & Clerget-Froidevaux Marie-Stéphanie, October 2024 — The Downregulation of the Liver Lipid Metabolism Induced by Hypothyroidism in Male Mice: Metabolic Flexibility Favors Compensatory Mechanisms in White Adipose Tissue. In mammals, the maintenance of energy homeostasis relies on complex mechanisms requiring tight synchronization between… Int. J. Mol. Sci. vol. 25, n° 19, p. 10792
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms251910792
Djebar Morgane, Anselme Isabelle, Pezeron Guillaume, Bardet Pierre-Luc, Cantaut-Belarif Yasmine, Eschstruth Alexis, López-Santos Diego, Le Ribeuz Hélène, Jenett Arnim, Khoury Hanane, Veziers Joelle, Parmentier Caroline, Hirschler Aurélie, Carapito Christine, Bachmann-Gagescu Ruxandra et al., October 2024 — Astrogliosis and neuroinflammation underlie scoliosis upon cilia dysfunction. Cilia defects lead to scoliosis in zebrafish, but the underlying pathogenic mechanisms are poorly understood and may diverge… eLife vol. 13, , RP96831
ISSN
2050-084X
https://dx.doi.org/10.7554/eLife.96831.3
Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, September 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
ISSN
1879-1514
https://dx.doi.org/10.1016/j.aquatox.2024.107081
Louis Emeric, Fu Liezhen, Shi Yun-Bo & Sachs Laurent M, September 2024 — Functions and Mechanism of Thyroid Hormone Receptor Action During Amphibian Development. Abstract Thyroid hormones and their receptors (TRs) play critical roles during vertebrate development. One of the most dramatic… Endocrinology vol. 165, n° 11, bqae137
ISSN
1945-7170
https://dx.doi.org/10.1210/endocr/bqae137
Aouci Rym, Fontaine Anastasia, Vion Amïn, Belz Lou, Levi Giovanni & Narboux-Nême Nicolas, July 2024 — The Antidepressant Action of Fluoxetine Involves the Inhibition of Dlx5/6 in Cortical GABAergic Neurons through a TrkB-Dependent Pathway. Major depressive disorder (MDD) is a complex and devastating illness that affects people of all ages. Despite the large use of… Cells vol. 13, n° 15, p. 1262
ISSN
2073-4409
https://dx.doi.org/10.3390/cells13151262
Valcárcel-Hernández Víctor, Vancamp Pieter, Butruille Lucile, Remaud Sylvie & Guadaño-Ferraz Ana, June 2024 — Combined deletion of Mct8 and Dio2 impairs SVZ neurogliogenesis and olfactory function in adult mice. Within the adult mouse subventricular zone (SVZ), neural stem cells (NSCs) produce neuroblasts and oligodendrocyte precursor… Neurobiology of Disease vol. 199, , p. 106572
ISSN
1095-953X
https://dx.doi.org/10.1016/j.nbd.2024.106572
Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, June 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2024.108861
Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., March 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2024.1360188
Vom Saal Frederick S., Antoniou Michael, Belcher Scott M., Bergman Ake, Bhandari Ramji K., Birnbaum Linda S., Cohen Aly, Collins Terrence J., Demeneix Barbara, Fine Anne Marie, Flaws Jodi A., Gayrard Veronique, Goodson William H., Gore Andrea C., Heindel Jerrold J. et al., March 2024 — The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA). BACKGROUND: The European Food Safety Authority (EFSA) recommended lowering their estimated tolerable daily intake (TDI) for… Environmental Health Perspectives vol. 132, n° 4, p. 45001
ISSN
1552-9924
https://dx.doi.org/10.1289/EHP13812
Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., January 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-023-43012-9
Rousseau Karine, Girardot Fabrice, Parmentier Caroline & Tostivint Hervé, January 2024 — The caudal neurosecretory system: a still enigmatic second neuroendocrine complex in fish. The caudal neurosecretory system (CNSS) is a neuroendocrine complex, whose existence is specific to fishes. In teleosts, it… Neuroendocrinology , ,
ISSN
1423-0194
https://dx.doi.org/10.1159/000536270
Valcárcel-Hernández Victor, Mayerl Steffen, Guadaño-Ferraz Ana & Remaud Sylvie, 2024 — Thyroid hormone action in adult neurogliogenic niches: the known and unknown. Over the last decades, thyroid hormones (THs) signaling has been established as a key signaling cue for the proper maintenance… Frontiers in Endocrinology vol. 15, , p. 1347802
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2024.1347802
Anoud M., Delagoutte E., Helleu Q., Brion A., Duvernois-Berthet E., As M., Marques X., Lamribet K., Senamaud C., Jourdren L., Adrait A., Heinrich S., Toutirais G., Hamlaoui S., Gropplero G. et al., January 2024 — Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation. Tardigrades, microscopic animals found in virtually all ecosystems, are renowned for their remarkable ability to withstand… eLife , ,
https://dx.doi.org/10.7554/eLife.92621.1
Mayeux Franck, Buisine Nicolas, Fayol Olivier & Uguen Patricia, 2024 — Transcriptional activation of candidate paused genes after partial hepatectomy. Partial hepatectomy is a model of acute liver injury that is known to induce a strong reprogrammation of gene expression… microPublication Biology vol. 2024, ,
ISSN
2578-9430
https://dx.doi.org/10.17912/micropub.biology.001160
F??nichel Patrick, Todaka Emiko, Etzel Ruth A., Chan Chang-Chuan, Barouki Robert, Chevalier Nicolas, Fini Jean-Baptiste, Poore Kirsten R., Sakabe Kou, Siroux Valerie, Yamamoto Midori & Mori Chisato, 2024 — Call to introduce environmental preventive medicine courses to the medical curriculum. An initial experience of an education program at the Faculty of Medicine of Nice, University of Côte d’Azur. Frontiers in Medicine vol. 11, , p. 1412674
ISSN
2296-858X
https://dx.doi.org/10.3389/fmed.2024.1412674
Pesce Elise, Garde Marion, Rigolet Muriel, Tindall Andrew J., Lemkine Gregory F., Baumann Lisa A., Sachs Laurent M. & Du Pasquier David, December 2023 — A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka. Identifying endocrine disrupting chemicals in order to limit their usage is a priority and required according to the European… Environ. Sci. Technol. , ,
ISSN
1520-5851
https://dx.doi.org/10.1021/acs.est.3c05515
Etienne Marchand, Fabienne Petit, Fabrice Alliot, Hélène Blanchoud, David Costantini, Elodie Guigon, Nicolas Martin, Sira Traore & Aurélie Goutte, December 2023 — Contrasted Antibiotics and Pesticides Impregnation in Fish Exposed in situ to Urban Effluents: A 20-Day Caging Experiment. Urban freshwater ecosystems receive a wide array of organic pollutants through wastewater treatment plant (WWTP) discharges and… Environ Toxicol Chem , ,
ISSN
1552-8618
https://dx.doi.org/10.1002/etc.5810
Rannaud-Bartaire Patricia, Demeneix Barbara A. & Fini Jean-Baptiste, December 2023 — Pressures of the urban environment on the endocrine system: Adverse effects and adaptation. With an increasing collective awareness of the rapid environmental changes, questions and theories regarding the adaptability… Mol. Cell. Endocrinol. , , p. 112125
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2023.112125
Krief Sabrina, Spirhanzlova Petra, Masi Shelly, Couturier Chloé, Okwir Eric, Asalu Edward, Bustamante Paco & Costantini David, November 2023 — High urinary oxidative DNA damage in wild chimpanzees ranging in proximity of agricultural fields in Sebitoli area, Uganda. Agriculture expansion is a major cause of habitat loss and exposure to phytochemical pollution for non-human primates. In… vol. 30, n° 51, p. 110600-110611
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-023-30187-3