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Physiologie moléculaire et adaptation
UMR 7221

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Aouci Rym, Fontaine Anastasia, Vion Amïn, Belz Lou, Levi Giovanni & Narboux-Nême Nicolas, July 2024 — The Antidepressant Action of Fluoxetine Involves the Inhibition of Dlx5/6 in Cortical GABAergic Neurons through a TrkB-Dependent Pathway. Major depressive disorder (MDD) is a complex and devastating illness that affects people of all ages. Despite the large use of… Cells vol. 13, n° 15, p. 1262
ISSN
2073-4409
https://dx.doi.org/10.3390/cells13151262
Levi Giovanni, Narboux-Nême Nicolas & Cohen-Solal Martine, October 2022 — DLX Genes in the Development and Maintenance of the Vertebrate Skeleton: Implications for Human Pathologies. Skeletal shape and mechanical properties define, to a large extent, vertebrate morphology and physical capacities. During… Cells vol. 11, n° 20, p. 3277
ISSN
2073-4409
https://dx.doi.org/10.3390/cells11203277
Aouci Rym, El Soudany Mey, Maakoul Zakaria, Fontaine Anastasia, Kurihara Hiroki, Levi Giovanni & Narboux-Nême Nicolas, May 2022 — Dlx5/6 Expression Levels in Mouse GABAergic Neurons Regulate Adult Parvalbumin Neuronal Density and Anxiety/Compulsive Behaviours. Neuronal circuits integrating Parvalbumin-positive GABAergic inhibitory interneurons (PV) are essential for normal brain… Cells vol. 11, n° 11, p. 1739
ISSN
2073-4409
https://dx.doi.org/10.3390/cells11111739
Mullen Rachel D., Bellessort Brice, Levi Giovanni & Behringer Richard R., 2022 — Distal-less homeobox genes Dlx5/6 regulate Müllerian duct regression. Dlx5 and Dlx6 encode distal-less homeodomain transcription factors that are present in the genome as a linked pair at a single… Frontiers in Endocrinology vol. 13, , p. 916173
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2022.916173
Levi Giovanni, de Lombares Camille, Giuliani Cristina, Iannuzzi Vincenzo, Aouci Rym, Garagnani Paolo, Franceschi Claudio, Grimaud-Hervé Dominique & Narboux-Nême Nicolas, 2021 — DLX 5/6 GABAergic expression affects social vocalization: implications for human evolution. DLX 5 and DLX6 are two closely related transcription factors involved in brain development and in GABAergic differentiation… Mol. Biol. Evol. , , msab181
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msab181
de Lombares Camille, Heude Eglantine, Alfama Gladys, Fontaine Anastasia, Hassouna Rim, Vernochet Cécile, deChaumont Fabrice, Olivo-Marin Christophe, Ey Elodie, Parnaudeau Sébastien, Tronche François, Bourgeron Thomas, Luquet Serge, Levi Giovanni & Narboux-Nême Nicolas, September 2019 — Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan. Aging (Albany NY) vol. 11, n° 17, p. 6638-6656
ISSN
1945-4589
https://dx.doi.org/10.18632/aging.102141
Narboux-Neme Nicolas, Ekker Marc, Levi Giovanni & Heude Eglantine, 2019 — Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border. PLoS ONE vol. 14, n° 3, e0214063
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0214063
Shimizu Miki, Narboux-Nême Nicolas, Gitton Yorick, deLombares Camille, Fontaine Anastasia, Alfama Gladys, Kitazawa Taro, Kawamura Yumiko, Heude Eglantine, Marshall Lindsey, Higashiyama Hiroki, Wada Youichiro, Kurihara Yukiko, Kurihara Hiroki & Levi Giovanni, October 2018 — Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells. Sci Rep vol. 8, n° 1, p. 14975
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-018-33207-2
Bellessort Brice, Bachelot Anne, Grouthier Virginie, DeLombares Camille, Narboux-Neme Nicolas, Garagnani Paolo, Pirazzini Chiara, Astigiano Simonetta, Mastracci Luca, Fontaine Anastasia, Alfama Gladys, Duvernois-Berthet Evelyne & Levi Giovanni, 2018 — Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain. J Pain Res vol. 11, , p. 715-725
ISSN
1178-7090
https://dx.doi.org/10.2147/JPR.S163611
Bellessort Brice, Le Cardinal Marine, Bachelot Anne, Narboux-Nême Nicolas, Garagnani Paolo, Pirazzini Chiara, Barbieri Ottavia, Mastracci Luca, Jonchere Vincent, Duvernois-Berthet Evelyne, Fontaine Anastasia, Alfama Gladys & Levi Giovanni, January 2016 — Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis. Hum. Mol. Genet. vol. 25, n° 1, p. 97-108
ISSN
1460-2083
https://dx.doi.org/10.1093/hmg/ddv452
Bellessort Brice, Bachelot Anne, Heude Églantine, Alfama Gladys, Fontaine Anastasia, Le Cardinal Marine, Treier Mathias & Levi Giovanni, June 2015 — Role of Foxl2 in uterine maturation and function. Hum. Mol. Genet. vol. 24, n° 11, p. 3092-3103
ISSN
1460-2083
https://dx.doi.org/10.1093/hmg/ddv061
Kitazawa Taro, Fujisawa Kou, Narboux-Nême Nicolas, Arima Yuichiro, Kawamura Yumiko, Inoue Tsuyoshi, Wada Youichiro, Kohro Takahide, Aburatani Hiroyuki, Kodama Tatsuhiko, Kim Ki-Sung, Sato Takahiro, Uchijima Yasunobu, Maeda Kazuhiro, Miyagawa-Tomita Sachiko et al., June 2015 — Distinct effects of Hoxa2 overexpression in cranial neural crest populations reveal that the mammalian hyomandibular-ceratohyal boundary maps within the styloid process. Dev. Biol. vol. 402, n° 2, p. 162-174
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2015.04.007
Kitazawa Taro, Takechi Masaki, Hirasawa Tatsuya, Adachi Noritaka, Narboux-Nême Nicolas, Kume Hideaki, Maeda Kazuhiro, Hirai Tamami, Miyagawa-Tomita Sachiko, Kurihara Yukiko, Hitomi Jiro, Levi Giovanni, Kuratani Shigeru & Kurihara Hiroki, April 2015 — Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids. Nat Commun vol. 6, , p. 6853
ISSN
2041-1723
https://dx.doi.org/10.1038/ncomms7853
Heude Églantine, Bellessort Brice, Fontaine Anastasia, Hamazaki Manatsu, Treier Anna-Corina, Treier Mathias, Levi Giovanni & Narboux-Nême Nicolas, March 2015 — Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome. Hum. Mol. Genet. vol. 24, n° 6, p. 1670-1681
ISSN
1460-2083
https://dx.doi.org/10.1093/hmg/ddu579
Krief Sabrina, Krief Jean-Michel, Seguya Andrew, Couly Gérard & Levi Giovanni, August 2014 — Facial dysplasia in wild chimpanzees. J. Med. Primatol. vol. 43, n° 4, p. 280-283
ISSN
1600-0684
https://dx.doi.org/10.1111/jmp.12129
Kim Ki-Sung, Arima Yuichiro, Kitazawa Taro, Nishiyama Koichi, Asai Rieko, Uchijima Yasunobu, Sato Takahiro, Levi Giovanni, Kitanaka Sachiko, Igarashi Takashi, Kurihara Yukiko & Kurihara Hiroki, December 2013 — Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms. Mech. Dev. vol. 130, n° 11, p. 553-566
ISSN
1872-6356
https://dx.doi.org/10.1016/j.mod.2013.07.005
Vieux-Rochas Maxence, Bouhali Kamal, Mantero Stefano, Garaffo Giulia, Provero Paolo, Astigiano Simonetta, Barbieri Ottavia, Caratozzolo Mariano F., Tullo Apollonia, Guerrini Luisa, Lallemand Yvan, Robert Benoît, Levi Giovanni & Merlo Giorgio R., 2013 — BMP -mediated functional cooperation between Dlx5;Dlx6 and Msx1;Msx2 during mammalian limb development. PLoS ONE vol. 8, n° 1, e51700
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0051700
Gitton Yorick, Narboux-Nême Nicolas & Levi Giovanni, 2013 — Transitory expression of Dlx5 and Dlx6 in maxillary arch epithelial precursors is essential for upper jaw morphogenesis. F1000Res vol. 2, , p. 261
ISSN
2046-1402
https://dx.doi.org/10.12688/f1000research.2-261.v3
Caburet Sandrine, Zavadakova Petra, Ben-Neriah Ziva, Bouhali Kamal, Dipietromaria Aurélie, Charon Céline, Besse Céline, Laissue Paul, Chalifa-Caspi Vered, Christin-Maitre Sophie, Vaiman Daniel, Levi Giovanni, Veitia Reiner A. & Fellous Marc, 2012 — Genome-wide linkage in a highly consanguineous pedigree reveals two novel loci on chromosome 7 for non-syndromic familial Premature Ovarian Failure. PLoS ONE vol. 7, n° 3, e33412
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0033412
Heude Eglantine, Rivals Isabelle, Couly Gérard & Levi Giovanni, August 2011 — Masticatory muscle defects in hemifacial microsomia: a new embryological concept. Am. J. Med. Genet. A vol. 155A, n° 8, p. 1991-1995
ISSN
1552-4833
https://dx.doi.org/10.1002/ajmg.a.34095
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