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Physiologie moléculaire et adaptation
UMR 7221

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Krief Sabrina, Spirhanzlova Petra, Masi Shelly, Couturier Chloé, Okwir Eric, Asalu Edward, Bustamante Paco & Costantini David, novembre 2023 — High urinary oxidative DNA damage in wild chimpanzees ranging in proximity of agricultural fields in Sebitoli area, Uganda. Agriculture expansion is a major cause of habitat loss and exposure to phytochemical pollution for non-human primates. In… vol. 30, n° 51, p. 110600-110611
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-023-30187-3
Butruille L., Jubin P., Martin E., Aigrot M. S., Lhomme M., Fini J. B., Demeneix B., Stankoff B., Lubetzki C., Zalc B. & Remaud S., septembre 2023 — Deleterious functional consequences of perfluoroalkyl substances accumulation into the myelin sheath. Exposure to persistent organic pollutants during the perinatal period is of particular concern because of the potential… vol. 180, , p. 108211
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2023.108211
Derakhshan Arash, Shu Huan, Broeren Maarten A. C., Kortenkamp Andreas, Lindh Christian H., Demeneix Barbara, Peeters Robin P., Bornehag Carl-Gustaf & Korevaar Tim I. M., juillet 2023 — Association of endocrine disrupting chemicals exposure with human chorionic gonadotropin concentrations in pregnancy. BACKGROUND: Human chorionic gonadotropin (hCG) is produced by the placenta and plays an essential role in the maintenance of… Environ Int vol. 178, , p. 108091
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2023.108091
Vancamp Pieter & Remaud Sylvie, mars 2023 — Developmental exposure to thyroid disruptors: misprogramming of the brain’s stem cells in later life?. Neural Regen Res vol. 18, n° 3, p. 527-528
ISSN
1673-5374
https://dx.doi.org/10.4103/1673-5374.346053
Pasquier Elodie, Viguié Catherine, Fini Jean-Baptiste, Mhaouty-Kodja Sakina & Michel-Caillet Cécile, mars 2023 — Limits of the regulatory evaluation of resorcinol as a thyroid disruptor: When limited experimental data challenge established effects in humans. Severe hypothyroidism has been reported in humans during resorcinol therapeutic use. However, available data highlight… Environ Res vol. 222, , p. 115330
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2023.115330
Sapounidou Maria, Andersson Patrik L., Leemans Michelle, Fini Jean-Baptiste, Demeneix Barbara, Rüegg Joëlle, Bornehag Carl-Gustaf & Gennings Chris, mars 2023 — From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data. Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in… Toxics vol. 11, n° 4, p. 331
ISSN
2305-6304
https://dx.doi.org/10.3390/toxics11040331
Gaillard Anne-Laure, Mohamad Teddy, Quan Feng B., de Cian Anne, Mosimann Christian, Tostivint Hervé & Pézeron Guillaume, mars 2023 — Urp1 and Urp2 act redundantly to maintain spine shape in zebrafish larvae. Developmental Biology , , S0012160623000180
ISSN
00121606
https://dx.doi.org/10.1016/j.ydbio.2023.01.010
Butruille Lucile, Sébillot Anthony, Ávila Katia, Vancamp Pieter, Demeneix Barbara A., Pifferi Fabien & Remaud Sylvie, mars 2023 — Increased oligodendrogenesis and myelination in the subventricular zone of aged mice and gray mouse lemurs. The adult rodent subventricular zone (SVZ) generates neural stem cells (NSCs) throughout life that migrate to the olfactory… Stem Cell Reports vol. 18, n° 2, p. 534-554
ISSN
2213-6711
https://dx.doi.org/10.1016/j.stemcr.2022.12.015
Rodríguez-Carrillo Andrea, Mustieles Vicente, Salamanca-Fernández Elena, Olivas-Martínez Alicia, Suárez Beatriz, Bajard Lola, Baken Kirsten, Blaha Ludek, Bonefeld-Jørgensen Eva Cecilie, Couderq Stephan, D’Cruz ShereenCynthia, Fini Jean-Baptiste, Govarts Eva, Gundacker Claudia, Hernández Antonio F. et al., mars 2023 — Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge. Human biomonitoring (HBM) studies have highlighted widespread daily exposure to environmental chemicals. Some of these are… Int J Hyg Environ Health vol. 249, , p. 114140
ISSN
1618-131X
https://dx.doi.org/10.1016/j.ijheh.2023.114140
Leemans Michelle, Spirhanzlova Petra, Couderq Stephan, LeMével Sébastien, Grimaldi Alexis, Duvernois-Berthet Evelyne, Demeneix Barbara & Fini Jean-Baptiste, janvier 2023 — A Mixture of Chemicals Found in Human Amniotic Fluid Disrupts Brain Gene Expression and Behavior in Xenopus laevis. Thyroid hormones (TH) are essential for normal brain development, influencing neural cell differentiation, migration, and… Int J Mol Sci. vol. 24, n° 3, p. 2588
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms24032588
Vancamp Pieter, Butruille Lucile, Herranen Anni, Boelen Anita, Fini Jean-Baptiste, Demeneix Barbara A. & Remaud Sylvie, janvier 2023 — Transient developmental exposure to low doses of bisphenol F negatively affects neurogliogenesis and olfactory behaviour in adult mice. Neural stem cells in the murine subventricular zone (SVZ) reactivate during postnatal development to generate neurons and glia… Environ Int . vol. 172, , p. 107770
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2023.107770
Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2023.1208182
Ullrich Simon, Leidescher Susanne, Feodorova Yana, Thanisch Katharina, Fini Jean-Baptiste, Kaspers Bernd, Weber Frank, Markova Boyka, Führer Dagmar, Romitti Mirian, Krebs Stefan, Blum Helmut, Leonhardt Heinrich, Costagliola Sabine, Heuer Heike et al., 2023 — The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes. Abnormalities are indispensable for studying normal biological processes and mechanisms. In the present work, we draw attention… vol. 11, , p. 1265407
ISSN
2296-634X
https://dx.doi.org/10.3389/fcell.2023.1265407
Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Andersen Helle Raun, David Arthur, Freire Carmen, Fernández Mariana F., D’Cruz Shereen Cynthia, Reina-Pérez Iris, Fini Jean-Baptiste & Blaha Ludek, novembre 2022 — Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence. BACKGROUND : Pyrethroid metabolites are widely detectable in urine from the general population, including pregnant women and… Environmental Research vol. 214, , p. 113935
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2022.113935
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
ISSN
1664-8021
https://dx.doi.org/10.3389/fgene.2022.996826
Levi Giovanni, Narboux-Nême Nicolas & Cohen-Solal Martine, octobre 2022 — DLX Genes in the Development and Maintenance of the Vertebrate Skeleton: Implications for Human Pathologies. Skeletal shape and mechanical properties define, to a large extent, vertebrate morphology and physical capacities. During… Cells vol. 11, n° 20, p. 3277
ISSN
2073-4409
https://dx.doi.org/10.3390/cells11203277
Chamas Lamis, Seugnet Isabelle, Poirier Roseline, Clerget-Froidevaux Marie-Stéphanie & Enderlin Valérie, octobre 2022 — A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. Adult-onset hypothyroidism is associated with learning and cognitive dysfunctions, which may be related to alterations in… International Journal of Molecular Sciences vol. 23, n° 19, p. 11938
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms231911938
Derakhshan Arash, Kortenkamp Andreas, Shu Huan, Broeren Maarten A. C., Lindh Christian H., Peeters Robin P., Bornehag Carl-Gustaf, Demeneix Barbara & Korevaar Tim I. M., septembre 2022 — Association of per- and polyfluoroalkyl substances with thyroid homeostasis during pregnancy in the SELMA study. OBJECTIVES : To investigate the association of exposure to per- and polyfluoroalkyl substances (PFAS) during early… Environ Int . vol. 167, , p. 107420
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2022.107420
Boisard Julie, Duvernois-Berthet Evelyne, Duval Linda, Schrével Joseph, Guillou Laure, Labat Amandine, Le Panse Sophie, Prensier Gérard, Ponger Loïc & Florent Isabelle, juillet 2022 — Marine gregarine genomes reveal the breadth of apicomplexan diversity with a partially conserved glideosome machinery. Our current view of the evolutionary history, coding and adaptive capacities of Apicomplexa, protozoan parasites of a wide… BMC Genomics vol. 23, n° 1, p. 485
ISSN
1471-2164
https://dx.doi.org/10.1186/s12864-022-08700-8
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  • Gladys ALFAMA
  • Rym AOUCI
  • Anne BACHELOT
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • David COSTANTINI
  • Stephan COUDERQ
  • Camille DE LOMBARES
  • Barbara DEMENEIX
  • Evelyne DUVERNOIS-BERTHET
  • Jean-Baptiste FINI
  • Anastasia FONTAINE
  • Anne-Laure GAILLARD
  • Fabrice GIRARDOT
  • Anni HERRANEN
  • Eglantine HEUDE
  • Karine LE BLAY
  • Michelle LEEMANS
  • Sébastien LE MEVEL
  • Giovanni LEVI
  • Nicolas NARBOUX-NÊME
  • Louise PERICARD
  • Guillaume PÉZERON
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Karine ROUSSEAU
  • Laurent SACHS
  • Manrico SEBASTIANO
  • Anthony SEBILLOT
  • Isabelle SEUGNET
  • Hervé TOSTIVINT
  • Alicia TRIBONDEAU
  • Pieter VANCAMP

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