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Physiologie moléculaire et adaptation
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Carrara Mathieu, Gaillard Anne-Laure, Brion Alice, Duvernois-Berthet Evelyne, Giovannangeli Carine, Concordet Jean-Paul & Pézeron Guillaume, mars 2025 — Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish. Double strand breaks (DSBs) are the most deleterious DNA lesions as they frequently result in mutations when repaired by… Scientific Reports vol. 15, n° 1, p. 4886
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-025-88564-6
Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, octobre 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
ISSN
1879-1514
https://dx.doi.org/10.1016/j.aquatox.2024.107081
Louis Emeric, Fu Liezhen, Shi Yun-Bo & Sachs Laurent M, octobre 2024 — Functions and Mechanism of Thyroid Hormone Receptor Action During Amphibian Development. Abstract Thyroid hormones and their receptors (TRs) play critical roles during vertebrate development. One of the most dramatic… Endocrinology vol. 165, n° 11, bqae137
ISSN
1945-7170
https://dx.doi.org/10.1210/endocr/bqae137
Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, juillet 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2024.108861
Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mars 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2024.1360188
Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., janvier 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-023-43012-9
Anoud M., Delagoutte E., Helleu Q., Brion A., Duvernois-Berthet E., As M., Marques X., Lamribet K., Senamaud C., Jourdren L., Adrait A., Heinrich S., Toutirais G., Hamlaoui S., Gropplero G. et al., janvier 2024 — Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation. Tardigrades, microscopic animals found in virtually all ecosystems, are renowned for their remarkable ability to withstand… eLife , ,
https://dx.doi.org/10.7554/eLife.92621.1
Mayeux Franck, Buisine Nicolas, Fayol Olivier & Uguen Patricia, 2024 — Transcriptional activation of candidate paused genes after partial hepatectomy. Partial hepatectomy is a model of acute liver injury that is known to induce a strong reprogrammation of gene expression… microPublication Biology vol. 2024, ,
ISSN
2578-9430
https://dx.doi.org/10.17912/micropub.biology.001160
F??nichel Patrick, Todaka Emiko, Etzel Ruth A., Chan Chang-Chuan, Barouki Robert, Chevalier Nicolas, Fini Jean-Baptiste, Poore Kirsten R., Sakabe Kou, Siroux Valerie, Yamamoto Midori & Mori Chisato, 2024 — Call to introduce environmental preventive medicine courses to the medical curriculum. An initial experience of an education program at the Faculty of Medicine of Nice, University of Côte d’Azur. Frontiers in Medicine vol. 11, , p. 1412674
ISSN
2296-858X
https://dx.doi.org/10.3389/fmed.2024.1412674
Pesce Elise, Garde Marion, Rigolet Muriel, Tindall Andrew J., Lemkine Gregory F., Baumann Lisa A., Sachs Laurent M. & Du Pasquier David, décembre 2023 — A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka. Identifying endocrine disrupting chemicals in order to limit their usage is a priority and required according to the European… Environ. Sci. Technol. , ,
ISSN
1520-5851
https://dx.doi.org/10.1021/acs.est.3c05515
Rannaud-Bartaire Patricia, Demeneix Barbara A. & Fini Jean-Baptiste, décembre 2023 — Pressures of the urban environment on the endocrine system: Adverse effects and adaptation. With an increasing collective awareness of the rapid environmental changes, questions and theories regarding the adaptability… Mol. Cell. Endocrinol. , , p. 112125
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2023.112125
Spirhanzlova Petra, Couderq Stephan, Le Mével Sébastian, Leemans Michelle, Krief Sabrina, Mughal Bilal B., Demeneix Barbara A. & Fini Jean-Baptiste, juillet 2023 — Short and long term effects of chlorpyrifos on thyroid hormone axis and brain development in Xenopus laevis. INTRODUCTION: The extensive use of the insecticide chlorpyrifos (CPF) throughout the world has brought increased scrutiny on… Neuroendocrinology vol. 113, n° 12, p. 1298-1311
ISSN
1423-0194
https://dx.doi.org/10.1159/000525719
Pasquier Elodie, Viguié Catherine, Fini Jean-Baptiste, Mhaouty-Kodja Sakina & Michel-Caillet Cécile, mars 2023 — Limits of the regulatory evaluation of resorcinol as a thyroid disruptor: When limited experimental data challenge established effects in humans. Severe hypothyroidism has been reported in humans during resorcinol therapeutic use. However, available data highlight… Environ Res vol. 222, , p. 115330
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2023.115330
Sapounidou Maria, Andersson Patrik L., Leemans Michelle, Fini Jean-Baptiste, Demeneix Barbara, Rüegg Joëlle, Bornehag Carl-Gustaf & Gennings Chris, mars 2023 — From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data. Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in… Toxics vol. 11, n° 4, p. 331
ISSN
2305-6304
https://dx.doi.org/10.3390/toxics11040331
Rodríguez-Carrillo Andrea, Mustieles Vicente, Salamanca-Fernández Elena, Olivas-Martínez Alicia, Suárez Beatriz, Bajard Lola, Baken Kirsten, Blaha Ludek, Bonefeld-Jørgensen Eva Cecilie, Couderq Stephan, D’Cruz ShereenCynthia, Fini Jean-Baptiste, Govarts Eva, Gundacker Claudia, Hernández Antonio F. et al., mars 2023 — Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge. Human biomonitoring (HBM) studies have highlighted widespread daily exposure to environmental chemicals. Some of these are… Int J Hyg Environ Health vol. 249, , p. 114140
ISSN
1618-131X
https://dx.doi.org/10.1016/j.ijheh.2023.114140
Leemans Michelle, Spirhanzlova Petra, Couderq Stephan, LeMével Sébastien, Grimaldi Alexis, Duvernois-Berthet Evelyne, Demeneix Barbara & Fini Jean-Baptiste, janvier 2023 — A Mixture of Chemicals Found in Human Amniotic Fluid Disrupts Brain Gene Expression and Behavior in Xenopus laevis. Thyroid hormones (TH) are essential for normal brain development, influencing neural cell differentiation, migration, and… Int J Mol Sci. vol. 24, n° 3, p. 2588
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms24032588
Vancamp Pieter, Butruille Lucile, Herranen Anni, Boelen Anita, Fini Jean-Baptiste, Demeneix Barbara A. & Remaud Sylvie, janvier 2023 — Transient developmental exposure to low doses of bisphenol F negatively affects neurogliogenesis and olfactory behaviour in adult mice. Neural stem cells in the murine subventricular zone (SVZ) reactivate during postnatal development to generate neurons and glia… Environ Int . vol. 172, , p. 107770
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2023.107770
Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2023.1208182
Ullrich Simon, Leidescher Susanne, Feodorova Yana, Thanisch Katharina, Fini Jean-Baptiste, Kaspers Bernd, Weber Frank, Markova Boyka, Führer Dagmar, Romitti Mirian, Krebs Stefan, Blum Helmut, Leonhardt Heinrich, Costagliola Sabine, Heuer Heike et al., 2023 — The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes. Abnormalities are indispensable for studying normal biological processes and mechanisms. In the present work, we draw attention… vol. 11, , p. 1265407
ISSN
2296-634X
https://dx.doi.org/10.3389/fcell.2023.1265407
Rannaud-Bartaire Patricia & Fini Jean-Baptiste, 2023 — [Disruptors of thyroid hormones: Which consequences for human health and environment?]. Endocrine disruptors (EDs) of chemical origin are the subject of numerous studies, some of which have led to measures aimed at… Bio Aujourd'hui vol. 217, n° 3, p. 219-231
ISSN
2105-0686
https://dx.doi.org/10.1051/jbio/2023036
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  • Gladys ALFAMA
  • Anne BACHELOT
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Mathieu CARRARA
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • Stephan COUDERQ
  • Barbara DEMENEIX
  • Evelyne DUVERNOIS-BERTHET
  • Jean-Baptiste FINI
  • Anastasia FONTAINE
  • Anne-Laure GAILLARD
  • Fabrice GIRARDOT
  • Anni HERRANEN
  • Karine LE BLAY
  • Michelle LEEMANS
  • Sébastien LE MEVEL
  • Giovanni LEVI
  • Emeric LOUIS
  • Nicolas NARBOUX-NÊME
  • Louise PERICARD
  • Elise PESCE
  • Guillaume PÉZERON
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Laurent SACHS
  • Isabelle SEUGNET
  • Hervé TOSTIVINT
  • Alicia TRIBONDEAU
  • Pieter VANCAMP

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