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PhyMA est une Unité Mixte de Recherche CNRS-MNHN (UMR 7221).
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Physiologie moléculaire et adaptation
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Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mars 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2024.1360188
Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., janvier 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-023-43012-9
Mayeux Franck, Buisine Nicolas, Fayol Olivier & Uguen Patricia, 2024 — Transcriptional activation of candidate paused genes after partial hepatectomy. Partial hepatectomy is a model of acute liver injury that is known to induce a strong reprogrammation of gene expression… microPublication Biology vol. 2024, ,
ISSN
2578-9430
https://dx.doi.org/10.17912/micropub.biology.001160
Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2023.1208182
Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
ISSN
1664-8021
https://dx.doi.org/10.3389/fgene.2022.996826
Nguyen Duy, Buisine Nicolas, Fayol Olivier, Michels Annemieke A., Bensaude Olivier, Price David H. & Uguen Patricia, août 2021 — An alternative D. melanogaster 7SK snRNP. BACKGROUND: The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA… BMC Mol Cell Biol vol. 22, n° 1, p. 43
ISSN
2661-8850
https://dx.doi.org/10.1186/s12860-021-00381-7
Thambirajah Anita A., Wade Michael G., Verreault Jonathan, Buisine Nicolas, Alves Verônica A., Langlois Valerie S. & Helbing Caren C., août 2021 — Disruption by stealth - Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals. Thyroid hormones (THs) are important regulators of growth, development, and homeostasis of all vertebrates. There are many… Environ Res vol. 203, , p. 111906
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2021.111906
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
ISSN
1097-0177
https://dx.doi.org/10.1002/dvdy.304
Antoine-Lorquin Aymeric, Arensburger Peter, Arnaoty Ahmed, Asgari Sassan, Batailler Martine, Beauclair Linda, Belleannée Catherine, Buisine Nicolas, Coustham Vincent, Guyetant Serge, Helou Laura, Lecomte Thierry, Pitard Bruno, Stévant Isabelle & Bigot Yves, mai 2021 — Two repeated motifs enriched within some enhancers and origins of replication are bound by SETMAR isoforms in human colon cells. Setmar is a gene specific to simian genomes. The function(s) of its isoforms are poorly understood and their existence in… Genomics vol. 113, n° 3, p. 1589-1604
ISSN
1089-8646
https://dx.doi.org/10.1016/j.ygeno.2021.03.032
Helou Laura, Beauclair Linda, Dardente Hugues, Arensburger Peter, Buisine Nicolas, Jaszczyszyn Yan, Guillou Florian, Lecomte Thierry, Kentsis Alex & Bigot Yves, avril 2021 — The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition. PiggyBac(PB)-like elements (pble) are members of a eukaryotic DNA transposon family. This family is of interest to evolutionary… J Mol Biol vol. 433, n° 7, p. 166805
ISSN
1089-8638
https://dx.doi.org/10.1016/j.jmb.2020.166805
Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two… Cells vol. 10, n° 9, p. 2375
ISSN
2073-4409
https://dx.doi.org/10.3390/cells10092375
Kyono Yasuhiro, Raj Samhitha, Sifuentes Christopher J., Buisine Nicolas, Sachs Laurent & Denver Robert J., mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial… Dev. Biol. , ,
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2020.03.013
Kerdivel Gwenneg, Blugeon Corinne, Fund Cédric, Rigolet Muriel, Sachs Laurent M. & Buisine Nicolas, 2019 — Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl. Front Endocrinol (Lausanne) vol. 10, , p. 194
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2019.00194
Buisine Nicolas, Ruan Xiaoan, Ruan Yijun & Sachs Laurent M., août 2018 — Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues. Cold Spring Harb Protoc vol. 2018, n° 8, pdb.prot104620
ISSN
1559-6095
https://dx.doi.org/10.1101/pdb.prot104620
Buisine Nicolas, Ruan Xiaoan, Ruan Yijun & Sachs Laurent M., août 2018 — Chromatin Immunoprecipitation for Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues. Cold Spring Harb Protoc vol. 2018, n° 8, pdb.prot097725
ISSN
1559-6095
https://dx.doi.org/10.1101/pdb.prot097725
Buisine Nicolas, Kerdivel Gwenneg & Sachs Laurent M., 2018 — De Novo Transcriptomic Approach to Study Thyroid Hormone Receptor Action in Non-mammalian Models. Methods Mol. Biol. vol. 1801, , p. 265-285
ISSN
1940-6029
https://dx.doi.org/10.1007/978-1-4939-7902-8_21
Schneider Katelin A., Shewade Leena H., Buisine Nicolas, Sachs Laurent M. & Buchholz Daniel R., 2018 — A novel stress hormone response gene in tadpoles of Xenopus tropicalis. Gen. Comp. Endocrinol. vol. 260, , p. 107-114
ISSN
1095-6840
https://dx.doi.org/10.1016/j.ygcen.2018.01.006
Olvera A., Martyniuk C. J., Buisine N., Jiménez-Jacinto V., Sanchez-Flores A., Sachs L. M. & Orozco A., novembre 2017 — Differential transcriptome regulation by 3,5-T2 and 3’,3,5-T3 in brain and liver uncovers novel roles for thyroid hormones in tilapia. Sci Rep vol. 7, n° 1, p. 15043
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-017-14913-9
Nguyen Duy, Fayol Olivier, Buisine Nicolas, Lecorre Pierrette & Uguen Patricia, 2016 — Functional Interaction between HEXIM and Hedgehog Signaling during Drosophila Wing Development. Studying the dynamic of gene regulatory networks is essential in order to understand the specific signals and factors that… PLoS One vol. 11, n° 5, e0155438
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0155438
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  • Gladys ALFAMA
  • Evelyne DUVERNOIS-BERTHET
  • Sébastien LE MEVEL
  • Muriel RIGOLET
  • Laurent SACHS
  • Alicia TRIBONDEAU
  • (-) Nicolas BUISINE

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