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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Vancamp Pieter, Le Blay Karine, Butruille Lucile, Sébillot Anthony, Boelen Anita, Demeneix Barbara A. & Remaud Sylvie, March 2022 — Developmental thyroid disruption permanently affects the neuroglial output in the murine subventricular zone. Neural stem cells (NSCs) in the adult brain are a source of neural cells for brain injury repair. We investigated whether… Stem Cell Reports vol. 17, n° 3, p. 459-474
ISSN
2213-6711
https://dx.doi.org/10.1016/j.stemcr.2022.01.002
Vancamp Pieter, Gothié Jean-David, Luongo Cristina, Sébillot Anthony, Le Blay Karine, Butruille Lucile, Pagnin Maurice, Richardson Samantha J., Demeneix Barbara A. & Remaud Sylvie, 2019 — Gender-specific effects of transthyretin on neural stem cell fate in the subventricular zone of the adult mouse. Choroid plexus epithelial cells produce and secrete transthyretin (TTR). TTR binds and distributes thyroid hormone (TH) to… Sci Rep vol. 9, n° 1, p. 19689
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-019-56156-w
Le Blay Karine, Préau Laëtitia, Morvan-Dubois Ghislaine & Demeneix Barbara, 2018 — Expression of the inactivating deiodinase, Deiodinase 3, in the pre-metamorphic tadpole retina. PLoS ONE vol. 13, n° 4, e0195374
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0195374
Gothié J. D., Sébillot A., Luongo C., Legendre M., Nguyen Van C., Le Blay K., Perret-Jeanneret M., Remaud S. & Demeneix B. A., 2017 — Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism. OBJECTIVE : In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and… Mol Metab vol. 6, n° 11, p. 1551-1561
ISSN
2212-8778
https://dx.doi.org/10.1016/j.molmet.2017.08.003
Préau L., Le Blay K., Saint Paul E., Morvan-Dubois G. & Demeneix B. A., January 2016 — Differential thyroid hormone sensitivity of fast cycling progenitors in the neurogenic niches of tadpoles and juvenile frogs. Mol. Cell. Endocrinol. vol. 420, , p. 138-151
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2015.11.026
Vivien Céline, Scerbo Pierluigi, Girardot Fabrice, Le Blay Karine, Demeneix Barbara A. & Coen Laurent, March 2012 — Non-viral expression of mouse Oct4, Sox2, and Klf4 transcription factors efficiently reprograms tadpole muscle fibers in vivo. J. Biol. Chem. vol. 287, n° 10, p. 7427-7435
ISSN
1083-351X
https://dx.doi.org/10.1074/jbc.M111.324368
Vieux-Rochas Maxence, Coen Laurent, Sato Takahiro, Kurihara Yukiko, Gitton Yorick, Barbieri Ottavia, Le Blay Karine, Merlo Giorgio, Ekker Marc, Kurihara Hiroki, Janvier Philippe & Levi Giovanni, June 2007 — Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws. PLoS ONE vol. 2, n° 6, e510
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0000510
Coen Laurent, Le Blay Karine, Rowe Isaline & Demeneix Barbara A., May 2007 — Caspase-9 regulates apoptosis/proliferation balance during metamorphic brain remodeling in Xenopus. Proc. Natl. Acad. Sci. U.S.A. vol. 104, n° 20, p. 8502-8507
ISSN
0027-8424
https://dx.doi.org/10.1073/pnas.0608877104
Rowe Isaline, Le Blay Karine, Du Pasquier David, Palmier Karima, Levi Giovanni, Demeneix Barbara & Coen Laurent, May 2005 — Apoptosis of tail muscle during amphibian metamorphosis involves a caspase 9-dependent mechanism. Dev. Dyn. vol. 233, n° 1, p. 76-87
ISSN
1058-8388
https://dx.doi.org/10.1002/dvdy.20312
Rowe Isaline, Coen Laurent, Le Blay Karine, Le Mével Sébastien & Demeneix Barbara A., August 2002 — Autonomous regulation of muscle fibre fate during metamorphosis in Xenopus tropicalis. Dev. Dyn. vol. 224, n° 4, p. 381-390
ISSN
1058-8388
https://dx.doi.org/10.1002/dvdy.10117
Augusto L., Le Blay K., Auger G., Blanot D. & Chaby R., October 2001 — Interaction of bacterial lipopolysaccharide with mouse surfactant protein C inserted into lipid vesicles. Am. J. Physiol. Lung Cell Mol. Physiol. vol. 281, n° 4, L776--785
ISSN
1040-0605
https://dx.doi.org/10.1152/ajplung.2001.281.4.L776
Aussel L., Chaby R., Le Blay K., Kelly J., Thibault P., Perry M. B. & Caroff M., November 2000 — Chemical and serological characterization of the Bordetella hinzii lipopolysaccharides. FEBS Lett. vol. 485, n° 1, p. 40-46
ISSN
0014-5793
https://dx.doi.org/10.1016/s0014-5793(00)02181-5
Gueirard P., Le Blay K., Le Coustumier A., Chaby R. & Guiso N., May 1998 — Variation in Bordetella bronchiseptica lipopolysaccharide during human infection. FEMS Microbiol. Lett. vol. 162, n° 2, p. 331-337
ISSN
0378-1097
https://dx.doi.org/10.1111/j.1574-6968.1998.tb13017.x
Ancuta P., Fahmi H., Pons J. F., Le Blay K. & Chaby R., October 1997 — Involvement of the membrane form of tumour necrosis factor-alpha in lipopolysaccharide-induced priming of mouse peritoneal macrophages for enhanced nitric oxide response to lipopolysaccharide. Immunology vol. 92, n° 2, p. 259-266
ISSN
0019-2805
https://dx.doi.org/10.1046/j.1365-2567.1997.00338.x
Le Blay K., Gueirard P., Guiso N. & Chaby R., April 1997 — Antigenic polymorphism of the lipopolysaccharides from human and animal isolates of Bordetella bronchiseptica. Microbiology (Reading, Engl.) vol. 143 ( Pt 4), , p. 1433-1441
ISSN
1350-0872
https://dx.doi.org/10.1099/00221287-143-4-1433
Le Blay K., Caroff M., Blanchard F., Perry M. B. & Chaby R., April 1996 — Epitopes of Bordetella pertussis lipopolysaccharides as potential markers for typing of isolates with monoclonal antibodies. Microbiology (Reading, Engl.) vol. 142 ( Pt 4), , p. 971-978
ISSN
1350-0872
https://dx.doi.org/10.1099/00221287-142-4-971
Porter J. F., Connor K., van der Zee A., Reubsaet F., Ibsen P., Heron I., Chaby R., Le Blay K. & Donachie W., October 1995 — Characterisation of ovine Bordetella parapertussis isolates by analysis of specific endotoxin (lipopolysaccharide) epitopes, filamentous haemagglutinin production, cellular fatty acid composition and antibiotic sensitivity. FEMS Microbiol. Lett. vol. 132, n° 3, p. 195-201
ISSN
0378-1097
https://dx.doi.org/10.1111/j.1574-6968.1995.tb07833.x
Le Blay K., Caroff M., Richards J. C., Perry M. B. & Chaby R., September 1994 — Specific and cross-reacting monoclonal antibodies to Bordetella parapertussis and Bordetella bronchiseptica lipopolysaccharides. Microbiology (Reading, Engl.) vol. 140 ( Pt 9), , p. 2459-2465
ISSN
1350-0872
https://dx.doi.org/10.1099/13500872-140-9-2459
Lascu I., Le Blay K., Lacombe M. L., Presecan E. & Véron M., February 1993 — Assay of nucleoside diphosphate kinase in microtiter plates using a peroxidase-coupled method. Anal. Biochem. vol. 209, n° 1, p. 6-8
ISSN
0003-2697
https://dx.doi.org/10.1006/abio.1993.1075
Rose T., Glaser P., Surewicz W. K., Mantsch H. H., Reinstein J., Le Blay K., Gilles A. M. & Bârzu O., December 1991 — Structural and functional consequences of amino acid substitutions in the second conserved loop of Escherichia coli adenylate kinase. J. Biol. Chem. vol. 266, n° 35, p. 23654-23659
ISSN
0021-9258
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