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, 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide
pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
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1873-6424
, 2020 — Thyroid hormone regulation of neural stem cell fate: From development to ageing. In the vertebrate brain, neural stem cells (NSCs) generate both neuronal
and glial cells throughout life. However, their neuro… Acta Physiol (Oxf) vol. 228, n° 1, e13316
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1748-1716
, octobre 2022 — DLX Genes in the Development and Maintenance of the Vertebrate Skeleton: Implications for Human Pathologies. Skeletal shape and mechanical properties define, to a large extent,
vertebrate morphology and physical capacities. During… Cells vol. 11, n° 20, p. 3277
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2073-4409
, 2022 — Distal-less homeobox genes Dlx5/6 regulate Müllerian duct regression. Dlx5 and Dlx6 encode distal-less homeodomain transcription factors that
are present in the genome as a linked pair at a single… Frontiers in Endocrinology vol. 13, , p. 916173
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1664-2392
, 2021 — DLX 5/6 GABAergic expression affects social vocalization: implications for human evolution. DLX
5 and DLX6 are two closely related transcription factors involved in
brain development and in GABAergic differentiation… Mol. Biol. Evol. , , msab181
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1537-1719
, mai 2022 — Dlx5/6 Expression Levels in Mouse GABAergic Neurons Regulate Adult Parvalbumin Neuronal Density and Anxiety/Compulsive Behaviours. Neuronal circuits integrating Parvalbumin-positive GABAergic inhibitory
interneurons (PV) are essential for normal brain… Cells vol. 11, n° 11, p. 1739
ISSN
2073-4409
, octobre 2022 — A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. Adult-onset hypothyroidism is associated with learning and cognitive
dysfunctions, which may be related to alterations in… International Journal of Molecular Sciences vol. 23, n° 19, p. 11938
ISSN
1422-0067
, mars 2022 — Developmental thyroid disruption permanently affects the neuroglial output in the murine subventricular zone. Neural stem cells (NSCs) in the adult brain are a source of neural cells
for brain injury repair. We investigated whether… Stem Cell Reports vol. 17, n° 3, p. 459-474
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2213-6711
, 2024 — Thyroid hormone action in adult neurogliogenic niches: the known and unknown. Over the last decades, thyroid hormones (THs) signaling has been established as a key signaling cue for the proper maintenance… Frontiers in Endocrinology vol. 15, , p. 1347802
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1664-2392
, juin 2024 — Combined deletion of Mct8 and Dio2 impairs SVZ neurogliogenesis and olfactory function in adult mice. Within the adult mouse subventricular zone (SVZ), neural stem cells (NSCs) produce neuroblasts and oligodendrocyte precursor… Neurobiology of Disease vol. 199, , p. 106572
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1095-953X
, juillet 2024 — The Antidepressant Action of Fluoxetine Involves the Inhibition of Dlx5/6 in Cortical GABAergic Neurons through a TrkB-Dependent Pathway. Major depressive disorder (MDD) is a complex and devastating illness that affects people of all ages. Despite the large use of… Cells vol. 13, n° 15, p. 1262
ISSN
2073-4409
, octobre 2024 — The Downregulation of the Liver Lipid Metabolism Induced by Hypothyroidism in Male Mice: Metabolic Flexibility Favors Compensatory Mechanisms in White Adipose Tissue. In mammals, the maintenance of energy homeostasis relies on complex mechanisms requiring tight synchronization between… Int. J. Mol. Sci. vol. 25, n° 19, p. 10792
ISSN
1422-0067