Entité de rattachement
RODEO
Recherches
Habilité(e) à diriger des recherches
Spécialité
Endocrinologie moléculaire

Contact

Réseaux sociaux
Courriel
laurent.sachs [at] mnhn.fr
Téléphone
01 40 79 36 17
Fax
01 40 79 36 18
Adresse(s)

7 rue Cuvier
75005 Paris

Responsabilités dans l'unité

Directeur de l’UMR 7221 et Responsable de l’équipe RoDEo

Responsabilités hors unité

- Partenaire Project H2020 ERGO (2019-2023): Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation

- « Senior Editor » « Journal of Endocrinology » et « Journal of Molecular Endocrinology »

- Éditeur associé « Frontiers in Endocrinology » section « thyroid »

- Membre du comité éditorial de « cells »

- Membre du groupe de travail « Perturbateur Endocrinien » à l’ANSES (agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail)

- Membre du groupe de travail « Perturbation Thyroïdienne » à l’OCDE (Organisation de coopération et de développement économiques)

Enseignements

Co-responsable du module « Fonction thyroïdienne » dans le M2 Endocrinology et métabolisme de l’Université Paris-Saclay

Master Edocrinologie et Métabolisme. Paris Saclay

CV

sachs_laurent_umr7221_cv.pdf Format (Pdf) - 178.4 Ko

Publications

2024
  • Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, septembre 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
    ISSN
    1879-1514
    https://dx.doi.org/10.1016/j.aquatox.2024.107081
  • Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, juin 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
    ISSN
    1873-6750
    https://dx.doi.org/10.1016/j.envint.2024.108861
  • Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mars 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
    ISSN
    1664-2392
    https://dx.doi.org/10.3389/fendo.2024.1360188
  • Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., janvier 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
    ISSN
    2041-1723
    https://dx.doi.org/10.1038/s41467-023-43012-9
2023
  • Pesce Elise, Garde Marion, Rigolet Muriel, Tindall Andrew J., Lemkine Gregory F., Baumann Lisa A., Sachs Laurent M. & Du Pasquier David, décembre 2023 — A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka. Identifying endocrine disrupting chemicals in order to limit their usage is a priority and required according to the European… Environ. Sci. Technol. , ,
    ISSN
    1520-5851
    https://dx.doi.org/10.1021/acs.est.3c05515
  • Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
    ISSN
    1664-2392
    https://dx.doi.org/10.3389/fendo.2023.1208182
2022
  • Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
    ISSN
    1422-0067
    https://dx.doi.org/10.3390/ijms232213715
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
    ISSN
    1664-8021
    https://dx.doi.org/10.3389/fgene.2022.996826
  • Paul Bidisha, Sterner Zachary R., Buchholz Daniel R., Shi Yun-Bo & Sachs Laurent M., mai 2022 — Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes,… Cells vol. 11, n° 10, p. 1595
    ISSN
    2073-4409
    https://dx.doi.org/10.3390/cells11101595
2021
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
    ISSN
    1097-0177
    https://dx.doi.org/10.1002/dvdy.304
Voir toutes les publications