Les tutelles
CNRS-MNHN
Laurent SACHS
Entité de rattachement
RODEO
Recherches
Habilité(e) à diriger des recherches
Spécialité
Endocrinologie moléculaire
Contact
Réseaux sociaux
Courriel
Téléphone
01 40 79 36 17
Fax
01 40 79 36 18
Adresse(s)
7 rue Cuvier
75005 Paris
Responsabilités dans l'unité
Directeur de l'UMR 7221 et Responsable de l'équipe RoDEo
Responsabilités hors unité
- Partenaire Project H2020 ERGO (2019-2023): Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation
- "Senior Editor" "Journal of Endocrinology" et "Journal of Molecular Endocrinology"
- Éditeur associé "Frontiers in Endocrinology" section "thyroid"
- Membre du comité éditorial de "cells"
- Membre du groupe de travail "Perturbateur Endocrinien" à l'ANSES (agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail)
- Membre du groupe de travail "Perturbation Thyroïdienne" à l'OCDE (Organisation de coopération et de développement économiques)
Enseignement(s)
Co-responsable du module "Fonction thyroïdienne" dans le M2 Endocrinology et métabolisme de l'Université Paris-Saclay
Publications
2022
- Novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects... Frontiers in Genetics. Vol. 23, n° 22, p. 13715.,ISSN:1422-0067
- Octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and... International Journal of Molecular Sciences. Vol. 13, p. 996826.,ISSN:1664-8021
- Mai 2022 — Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes... Cells. Vol. 11, n° 10, p. 1595.,ISSN:2073-4409
2021
- Juin 2021 — The invention of aldosterone, how the past resurfaces in pediatric endocrinology. Sodium and water homeostasis are drastically modified at birth, in mammals, by the transition from aquatic life to terrestrial... Mol Cell Endocrinol. P. 111375.,ISSN:1872-8057
- Juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches... Dev Dyn. Vol. 250, n° 6, p. 779-787.,ISSN:1097-0177
- Mars 2021 — The Chicken and Egg Situation of Thyroid Hormone and Glucocorticoid Signaling during Postembryonic Development. Endocrinology. Vol. 162, n° 3, bqaa243.,ISSN:1945-7170
- 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two... Cells. Vol. 10, n° 9, p. 2375.,ISSN:2073-4409
- 2021 — Interdependence of Thyroid and Corticosteroid Signaling in Vertebrate Developmental Transitions. Post-embryonic acute developmental processes mainly allow the transition from one life stage in a specific ecological niche to... Front. Ecol. Evol. Vol. 9, p. 735487.,ISSN:2296-701X
2020
- Mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial... Dev. Biol.,ISSN:1095-564X
- Mars 2020 — ERGO : Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters. ERGO (EndocRine Guideline Optimization) is the acronym of a European Union-funded research and innovation action, that aims to... Int J Mol Sci. Vol. 21, n° 8, p. 2954.,ISSN:1422-0067