Entité de rattachement
RODEO
Recherches
Habilité(e) à diriger des recherches
Spécialité
Endocrinologie moléculaire

Contact

Réseaux sociaux
Courriel
laurent.sachs [at] mnhn.fr
Téléphone
01 40 79 36 17
Fax
01 40 79 36 18
Adresse(s)

7 rue Cuvier
75005 Paris

Responsabilités dans l'unité

Directeur de l'UMR 7221 et Responsable de l'équipe RoDEo

Responsabilités hors unité

- Partenaire Project H2020 ERGO (2019-2023): Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation

- "Senior Editor" "Journal of Endocrinology" et "Journal of Molecular Endocrinology"

- Éditeur associé "Frontiers in Endocrinology" section "thyroid"

- Membre du comité éditorial de "cells"

- Membre du groupe de travail "Perturbateur Endocrinien" à l'ANSES (agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail)

- Membre du groupe de travail "Perturbation Thyroïdienne" à l'OCDE (Organisation de coopération et de développement économiques)

Enseignements

Co-responsable du module "Fonction thyroïdienne" dans le M2 Endocrinology et métabolisme de l'Université Paris-Saclay

Master Edocrinologie et Métabolisme. Paris Saclay

CV

sachs_laurent_umr7221_cv.pdf Format (Pdf) - 178.4 Ko

Publications

2023
  • Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
    ISSN
    1664-2392
    https://dx.doi.org/10.3389/fendo.2023.1208182
2022
  • Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
    ISSN
    1422-0067
    https://dx.doi.org/10.3390/ijms232213715
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
    ISSN
    1664-8021
    https://dx.doi.org/10.3389/fgene.2022.996826
  • Paul Bidisha, Sterner Zachary R., Buchholz Daniel R., Shi Yun-Bo & Sachs Laurent M., mai 2022 — Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes,… Cells vol. 11, n° 10, p. 1595
    ISSN
    2073-4409
    https://dx.doi.org/10.3390/cells11101595
2021
  • Viengchareun Say, Pussard Eric, Castanet Mireille, Sachs Laurent M., Vu Thi An, Boileau Pascal, Lombès Marc & Martinerie Laetitia, juin 2021 — The invention of aldosterone, how the past resurfaces in pediatric endocrinology. Sodium and water homeostasis are drastically modified at birth, in mammals, by the transition from aquatic life to terrestrial… Mol Cell Endocrinol , , p. 111375
    ISSN
    1872-8057
    https://dx.doi.org/10.1016/j.mce.2021.111375
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
    ISSN
    1097-0177
    https://dx.doi.org/10.1002/dvdy.304
  • Dufour Sylvie & Sachs Laurent M., mars 2021 — The Chicken and Egg Situation of Thyroid Hormone and Glucocorticoid Signaling during Postembryonic Development. Endocrinology vol. 162, n° 3, bqaa243
    ISSN
    1945-7170
    https://dx.doi.org/10.1210/endocr/bqaa243
  • Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two… Cells vol. 10, n° 9, p. 2375
    ISSN
    2073-4409
    https://dx.doi.org/10.3390/cells10092375
  • Rousseau Karine, Dufour Sylvie & Sachs Laurent M., 2021 — Interdependence of Thyroid and Corticosteroid Signaling in Vertebrate Developmental Transitions. Post-embryonic acute developmental processes mainly allow the transition from one life stage in a specific ecological niche to… Front. Ecol. Evol. vol. 9, , p. 735487
    ISSN
    2296-701X
    https://dx.doi.org/10.3389/fevo.2021.735487
2020
  • Kyono Yasuhiro, Raj Samhitha, Sifuentes Christopher J., Buisine Nicolas, Sachs Laurent & Denver Robert J., mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial… Dev. Biol. , ,
    ISSN
    1095-564X
    https://dx.doi.org/10.1016/j.ydbio.2020.03.013
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