Laurent SACHS

Sachs © MNHN
Laurent SACHS
Directeur de Recherche
Chargé(e) d’enseignement
Entité de rattachement
RODEO
Recherches
Habilité(e) à diriger des recherches
Spécialité
Endocrinologie moléculaire

Contact

Réseaux sociaux
Téléphone
01 40 79 36 17
Fax
01 40 79 36 18
Adresse(s)

7 rue Cuvier
75005 Paris

Responsabilités dans l'unité

Directeur de l'UMR 7221 et Responsable de l'équipe RoDEo

Responsabilités hors unité

- Partenaire Project H2020 ERGO (2019-2023): Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation

- "Senior Editor" "Journal of Endocrinology" et "Journal of Molecular Endocrinology"

- Éditeur associé "Frontiers in Endocrinology" section "thyroid"

- Membre du comité éditorial de "cells"

- Membre du groupe de travail "Perturbateur Endocrinien" à l'ANSES (agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail)

- Membre du groupe de travail "Perturbation Thyroïdienne" à l'OCDE (Organisation de coopération et de développement économiques)

Enseignement(s)

Co-responsable du module "Fonction thyroïdienne" dans le M2 Endocrinology et métabolisme de l'Université Paris-Saclay

Master Edocrinologie et Métabolisme. Paris Saclay

CV

sachs_laurent_umr7221_cv.pdf Format (PDF) - 178.4 Ko

Publications

2022
  • Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., Novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects... Frontiers in Genetics. Vol. 23, n° 22, p. 13715.
    ISSN: 
    1422-0067
    https://dx.doi.org/10.3390/ijms232213715
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, Octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and... International Journal of Molecular Sciences. Vol. 13, p. 996826.
    ISSN: 
    1664-8021
    https://dx.doi.org/10.3389/fgene.2022.996826
  • Paul Bidisha, Sterner Zachary R., Buchholz Daniel R., Shi Yun-Bo & Sachs Laurent M., Mai 2022 — Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes... Cells. Vol. 11, n° 10, p. 1595.
    ISSN: 
    2073-4409
    https://dx.doi.org/10.3390/cells11101595
2021
  • Viengchareun Say, Pussard Eric, Castanet Mireille, Sachs Laurent M., Vu Thi An, Boileau Pascal, Lombès Marc & Martinerie Laetitia, Juin 2021 — The invention of aldosterone, how the past resurfaces in pediatric endocrinology. Sodium and water homeostasis are drastically modified at birth, in mammals, by the transition from aquatic life to terrestrial... Mol Cell Endocrinol. P. 111375.
    ISSN: 
    1872-8057
    https://dx.doi.org/10.1016/j.mce.2021.111375
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, Juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches... Dev Dyn. Vol. 250, n° 6, p. 779-787.
    ISSN: 
    1097-0177
    https://dx.doi.org/10.1002/dvdy.304
  • Dufour Sylvie & Sachs Laurent M., Mars 2021 — The Chicken and Egg Situation of Thyroid Hormone and Glucocorticoid Signaling during Postembryonic Development. Endocrinology. Vol. 162, n° 3, bqaa243.
    ISSN: 
    1945-7170
    https://dx.doi.org/10.1210/endocr/bqaa243
  • Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two... Cells. Vol. 10, n° 9, p. 2375.
    ISSN: 
    2073-4409
    https://dx.doi.org/10.3390/cells10092375
  • Rousseau Karine, Dufour Sylvie & Sachs Laurent M., 2021 — Interdependence of Thyroid and Corticosteroid Signaling in Vertebrate Developmental Transitions. Post-embryonic acute developmental processes mainly allow the transition from one life stage in a specific ecological niche to... Front. Ecol. Evol. Vol. 9, p. 735487.
    ISSN: 
    2296-701X
    https://dx.doi.org/10.3389/fevo.2021.735487
2020
  • Kyono Yasuhiro, Raj Samhitha, Sifuentes Christopher J., Buisine Nicolas, Sachs Laurent & Denver Robert J., Mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial... Dev. Biol.
    ISSN: 
    1095-564X
    https://dx.doi.org/10.1016/j.ydbio.2020.03.013
  • Holbech Henrik, Matthiessen Peter, Hansen Martin, Schüürmann Gerrit, Knapen Dries, Reuver Marieke, Flamant Frédéric, Sachs Laurent, Kloas Werner, Hilscherova Klara, Leonard Marc, Arning Jürgen, Strauss Volker, Iguchi Taisen & Baumann Lisa, Mars 2020 — ERGO : Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters. ERGO (EndocRine Guideline Optimization) is the acronym of a European Union-funded research and innovation action, that aims to... Int J Mol Sci. Vol. 21, n° 8, p. 2954.
    ISSN: 
    1422-0067
    https://dx.doi.org/10.3390/ijms21082954
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