Entité de rattachement
RODEO
Recherches
Habilité(e) à diriger des recherches
Spécialité
Endocrinologie moléculaire

Contact

Réseaux sociaux
Courriel
laurent.sachs [at] mnhn.fr
Téléphone
01 40 79 36 17
Fax
01 40 79 36 18
Adresse(s)

7 rue Cuvier
75005 Paris

Responsabilités hors unité

- Partenaire Project H2020 ERGO (2019-2023): Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation

- « Senior Editor » « Journal of Endocrinology » et « Journal of Molecular Endocrinology »

- Éditeur associé « Frontiers in Endocrinology » section « thyroid »

- Membre du comité éditorial de « cells »

- Membre du groupe de travail « Perturbateur Endocrinien » à l’ANSES (agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail)

- Membre du groupe de travail « Perturbation Thyroïdienne » à l’OCDE (Organisation de coopération et de développement économiques)

Enseignements

Co-responsable du module « Fonction thyroïdienne » dans le M2 Endocrinology et métabolisme de l’Université Paris-Saclay

Master Edocrinologie et Métabolisme. Paris Saclay

CV

sachs_laurent_umr7221_cv.pdf Format (Pdf) - 178.4 Ko

Publications

2026
  • Nashed Salomé, Uguen Patricia, Sachs Laurent M. & Buisine Nicolas, juin 2026 — VIJB: a companion of the JBROWSE genome browser for the visually impaired people. MOTIVATION: The availability of touch-sensitive and haptic devices has been a keystone development for the inclusion of… Bioinformatics , , btag396
    ISSN
    1367-4811
    https://dx.doi.org/10.1093/bioinformatics/btag396
  • Grimaldi Alexis, Rigolet Muriel, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mai 2026 — Crosstalk between corticosterone and triiodothyronine signaling in Xenopus tropicalis hindlimb buds. Thyroid hormone signaling has a wide range of biological effects involved in the control of homeostasis and development. In… Developmental Biology vol. 533, , p. 1-15
    ISSN
    1095-564X
    https://dx.doi.org/10.1016/j.ydbio.2026.02.001
  • Nashed Salomé, Louis Emeric, Buisine Nicolas & Sachs Laurent M., mai 2026 — Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown. Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches… Developmental Biology vol. 533, , p. 181-188
    ISSN
    1095-564X
    https://dx.doi.org/10.1016/j.ydbio.2026.02.013
  • Louis Emeric M., Fu Liezhen, Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — Protocol for streamlining genotyping of germline-transmissible mutants from genome editing by using a parallel qPCR-based index and R analysis. Targeted genome editing using CRISPR-Cas, ZFNs, or TALENs enables precise gene function studies but often produces point… STAR protocols vol. 7, n° 2, p. 104454
    ISSN
    2666-1667
    https://dx.doi.org/10.1016/j.xpro.2026.104454
  • Louis Emeric M., Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such… Cell & Bioscience vol. 16, n° 1, p. 26
    ISSN
    2045-3701
    https://dx.doi.org/10.1186/s13578-026-01537-8
2025
  • Dufour Sylvie, Sachs Laurent, Martin Patrick & Rousseau Karine, 2025 — [Metamorphoses in fishes and their endocrine regulations]. The most emblematic metamorphoses in the animal kingdom remain those of the caterpillar into a butterfly and the tadpole into a… Biologie Aujourd'hui vol. 219, n° 1, p. 37-50
    ISSN
    2105-0686
    https://dx.doi.org/10.1051/jbio/2025002
2024
  • Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, septembre 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
    ISSN
    1879-1514
    https://dx.doi.org/10.1016/j.aquatox.2024.107081
  • Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, juin 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
    ISSN
    1873-6750
    https://dx.doi.org/10.1016/j.envint.2024.108861
  • Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mars 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
    ISSN
    1664-2392
    https://dx.doi.org/10.3389/fendo.2024.1360188
  • Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., janvier 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
    ISSN
    2041-1723
    https://dx.doi.org/10.1038/s41467-023-43012-9
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