Laurent SACHS
Directeur de Recherche
Lecturer
Affiliation entity
RODEO
Researches
Accreditation to supervise research
Speciality
Molecular endocrinology
Contact
Social networks
E-mail
laurent.sachs [at] mnhn.fr
Phone
01 40 79 36 17
Fax
01 40 79 36 18
Address(es)
7 rue Cuvier
75005 Paris
Responsibilities inside unit
Directeur de l’UMR 7221 et Responsable de l’équipe RoDEo
Responsibilities outside unit
Project H2020 ERGO (2019-2023)
Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation
Teaching
Co-responsable du module “Fonction thyroïdienne” dans le M2 Endocrinology et métabolsime de l’université Paris-Saclay
CV
sachs_laurent_umr7221_cv.pdf
Format (Pdf) - 178.4 KB
Publications
2024
- , October 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081ISSN1879-1514
- , July 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861ISSN1873-6750
- , March 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188ISSN1664-2392
- , January 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579ISSN2041-1723
2023
- , December 2023 — A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka. Identifying endocrine disrupting chemicals in order to limit their usage is a priority and required according to the European… Environ. Sci. Technol. , ,ISSN1520-5851
- , 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182ISSN1664-2392
2022
- , December 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715ISSN1422-0067
- , October 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826ISSN1664-8021
- , May 2022 — Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis. In multicellular organisms, development is based in part on the integration of communication systems. Two neuroendocrine axes,… Cells vol. 11, n° 10, p. 1595ISSN2073-4409
2021
- , July 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787ISSN1097-0177