Laurent SACHS
Directeur de Recherche
Lecturer
Affiliation entity
RODEO
Researches
Accreditation to supervise research
Speciality
Molecular endocrinology
Contact
Social networks
E-mail
laurent.sachs [at] mnhn.fr
Phone
01 40 79 36 17
Fax
01 40 79 36 18
Address(es)
7 rue Cuvier
75005 Paris
Responsibilities outside unit
Project H2020 ERGO (2019-2023)
Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation
Teaching
Co-responsable du module “Fonction thyroïdienne” dans le M2 Endocrinology et métabolsime de l’université Paris-Saclay
CV
sachs_laurent_umr7221_cv.pdf
Format (Pdf) - 178.4 KB
Publications
2026
- , June 2026 — VIJB: a companion of the JBROWSE genome browser for the visually impaired people. MOTIVATION: The availability of touch-sensitive and haptic devices has been a keystone development for the inclusion of… Bioinformatics , , btag396ISSN1367-4811
- , May 2026 — Crosstalk between corticosterone and triiodothyronine signaling in Xenopus tropicalis hindlimb buds. Thyroid hormone signaling has a wide range of biological effects involved in the control of homeostasis and development. In… Developmental Biology vol. 533, , p. 1-15ISSN1095-564X
- , May 2026 — Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown. Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches… Developmental Biology vol. 533, , p. 181-188ISSN1095-564X
- , March 2026 — Protocol for streamlining genotyping of germline-transmissible mutants from genome editing by using a parallel qPCR-based index and R analysis. Targeted genome editing using CRISPR-Cas, ZFNs, or TALENs enables precise gene function studies but often produces point… STAR protocols vol. 7, n° 2, p. 104454ISSN2666-1667
- , March 2026 — The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such… Cell & Bioscience vol. 16, n° 1, p. 26ISSN2045-3701
2025
- , 2025 — [Metamorphoses in fishes and their endocrine regulations]. The most emblematic metamorphoses in the animal kingdom remain those of the caterpillar into a butterfly and the tadpole into a… Biologie Aujourd'hui vol. 219, n° 1, p. 37-50ISSN2105-0686
2024
- , September 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081ISSN1879-1514
- , June 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861ISSN1873-6750
- , March 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188ISSN1664-2392
- , January 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579ISSN2041-1723