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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Arivalagan Jaison, Yarra Tejaswi, Marie Benjamin, Sleight Victoria A., Duvernois-Berthet Evelyne, Clark Melody S., Marie Arul & Berland Sophie, 2017 — Insights from the Shell Proteome: Biomineralization to Adaptation. Bivalves have evolved a range of complex shell forming mechanisms that are reflected by their incredible diversity in shell… Sci Rep. vol. 34, n° 1, p. 66-77
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msw219
Qiao Qin, Le Manach Séverine, Sotton Benoit, Huet Hélène, Duvernois-Berthet Evelyne, Paris Alain, Duval Charlotte, Ponger Loïc, Marie Arul, Blond Alain, Mathéron Lucrèce, Vinh Joelle, Bolbach Gérard, Djediat Chakib, Bernard Cécile et al., 2016 — Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach. Sexual dimorphism describes the features that discriminate between the two sexes at various biological levels. Especially,… Sci Rep. vol. 6, , p. 32459
ISSN
2045-2322
https://dx.doi.org/10.1038/srep32459
Bussard Adrien, Corre Erwan, Hubas Cédric, Duvernois-Berthet Evelyne, Le Corguillé Gildas, Jourdren Laurent, Coulpier Fanny, Claquin Pascal & Lopez Pascal Jean, 2017 — Physiological adjustments and transcriptome reprogramming are involved in the acclimation to salinity gradients in diatoms. Salinity regimes in estuaries and coastal areas vary with river discharge patterns, seawater evaporation, the morphology of… Environ Microbiol. vol. 19, n° 3, p. 909-925
ISSN
1462-2920
https://dx.doi.org/10.1111/1462-2920.13398
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, October 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
ISSN
1664-8021
https://dx.doi.org/10.3389/fgene.2022.996826
Levi Giovanni, Narboux-Nême Nicolas & Cohen-Solal Martine, October 2022 — DLX Genes in the Development and Maintenance of the Vertebrate Skeleton: Implications for Human Pathologies. Skeletal shape and mechanical properties define, to a large extent, vertebrate morphology and physical capacities. During… Cells vol. 11, n° 20, p. 3277
ISSN
2073-4409
https://dx.doi.org/10.3390/cells11203277
Mullen Rachel D., Bellessort Brice, Levi Giovanni & Behringer Richard R., 2022 — Distal-less homeobox genes Dlx5/6 regulate Müllerian duct regression. Dlx5 and Dlx6 encode distal-less homeodomain transcription factors that are present in the genome as a linked pair at a single… Frontiers in Endocrinology vol. 13, , p. 916173
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2022.916173
Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., November 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Sebastiano Manrico, Costantini David, Eens Marcel, Pineau Kevin, Bustamante Paco & Chastel Olivier, June 2022 — Possible interaction between exposure to environmental contaminants and nutritional stress in promoting disease occurrence in seabirds from French Guiana: a review. Reg Environ Change vol. 22, n° 2, p. 63
ISSN
1436-3798, 1436-378X
https://dx.doi.org/10.1007/s10113-022-01914-2
Andersen Helle Raun, David Arthur, Freire Carmen, Fernández Mariana F., D’Cruz Shereen Cynthia, Reina-Pérez Iris, Fini Jean-Baptiste & Blaha Ludek, November 2022 — Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence. BACKGROUND : Pyrethroid metabolites are widely detectable in urine from the general population, including pregnant women and… Environmental Research vol. 214, , p. 113935
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2022.113935
Aouci Rym, El Soudany Mey, Maakoul Zakaria, Fontaine Anastasia, Kurihara Hiroki, Levi Giovanni & Narboux-Nême Nicolas, May 2022 — Dlx5/6 Expression Levels in Mouse GABAergic Neurons Regulate Adult Parvalbumin Neuronal Density and Anxiety/Compulsive Behaviours. Neuronal circuits integrating Parvalbumin-positive GABAergic inhibitory interneurons (PV) are essential for normal brain… Cells vol. 11, n° 11, p. 1739
ISSN
2073-4409
https://dx.doi.org/10.3390/cells11111739
Chamas Lamis, Seugnet Isabelle, Poirier Roseline, Clerget-Froidevaux Marie-Stéphanie & Enderlin Valérie, October 2022 — A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. Adult-onset hypothyroidism is associated with learning and cognitive dysfunctions, which may be related to alterations in… International Journal of Molecular Sciences vol. 23, n° 19, p. 11938
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms231911938
Alejevski Faredin, Leemans Michelle, Gaillard Anne-Laure, Leistenschneider David, de Flori Céline, Bougerol Marion, LeMével Sébastien, Herrel Anthony, Fini Jean-Baptiste, Pézeron Guillaume & Tostivint Hervé, August 2021 — Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. Urp1 and Urp2 are two neuropeptides of the urotensin II family identified in teleost fish and mainly expressed in… Open Biology vol. 11, n° 8, p. 210065
ISSN
2046-2441
https://dx.doi.org/10.1098/rsob.210065
Vancamp Pieter, Le Blay Karine, Butruille Lucile, Sébillot Anthony, Boelen Anita, Demeneix Barbara A. & Remaud Sylvie, March 2022 — Developmental thyroid disruption permanently affects the neuroglial output in the murine subventricular zone. Neural stem cells (NSCs) in the adult brain are a source of neural cells for brain injury repair. We investigated whether… Stem Cell Reports vol. 17, n° 3, p. 459-474
ISSN
2213-6711
https://dx.doi.org/10.1016/j.stemcr.2022.01.002
Couderq Stephan, Leemans Michelle & Fini Jean-Baptiste, May 2020 — Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models. Thyroid hormones (THs) play critical roles in profound changes in many vertebrates, notably in mammalian neurodevelopment,… Mol. Cell. Endocrinol. vol. 508, , p. 110779
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2020.110779
Levi Giovanni, de Lombares Camille, Giuliani Cristina, Iannuzzi Vincenzo, Aouci Rym, Garagnani Paolo, Franceschi Claudio, Grimaud-Hervé Dominique & Narboux-Nême Nicolas, 2021 — DLX 5/6 GABAergic expression affects social vocalization: implications for human evolution. DLX 5 and DLX6 are two closely related transcription factors involved in brain development and in GABAergic differentiation… Mol. Biol. Evol. , , msab181
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msab181
Costantini David, Masi Shelly, Rachid Lyna, Beltrame Marielle, Rohmer Mélanie & Krief Sabrina, 2021 — Mind the food: rapid changes in antioxidant content of diet affect oxidative status of chimpanzees. The link between dietary antioxidants and oxidative status has been studied extensively in humans. Surprisingly, comparative… Am J Physiol Regul Integr Comp Physiol vol. 320, n° 5, R728–R734
ISSN
1522-1490
https://dx.doi.org/10.1152/ajpregu.00003.2021
Marasco Valeria, Sebastiano Manrico, Costantini David, Pola Gianni & Fusani Leonida, 2021 — Controlled expression of the migratory phenotype affects oxidative status in birds. High caloric intake can increase production of reactive oxygen and nitrogen species. We examined whether the emergence of the… J Exp Biol vol. 224, , jeb233486
ISSN
1477-9145
https://dx.doi.org/10.1242/jeb.233486
Fritze Marcus, Puechmaille Sebastien J., Costantini David, Fickel Jörns, Voigt Christian C. & Czirják Gábor Á, 2021 — Determinants of defence strategies of a hibernating European bat species towards the fungal pathogen Pseudogymnoascus destructans. Pseudogymnoascus destructans (Pd), the causative agent of white-nose syndrome in North America, has decimated bat populations… Dev Comp Immunol vol. 119, , p. 104017
ISSN
1879-0089
https://dx.doi.org/10.1016/j.dci.2021.104017
Sebastiano Manrico, Canestrelli Daniele, Bisconti Roberta, Lavergne Anne, Pineau Kévin, Chastel Olivier, Lacoste Vincent & Costantini David, 2020 — Detection and Phylogenetic Characterization of a Novel Herpesvirus in Sooty Terns Onychoprion fuscatus. Since 2005, we have recorded annual episodes of alphaherpesvirus outbreaks in chicks of magnificent frigatebird Fregata… Front Vet Sci. vol. 7, , p. 567
ISSN
2297-1769
https://dx.doi.org/10.3389/fvets.2020.00567
Liparoto Anita, Canestrelli Daniele, Bisconti Roberta, Carere Claudio & Costantini David, 2020 — Biogeographic history moulds population differentiation in ageing of oxidative status in an amphibian. Regulation of oxidative status plays a substantial role in physiological ageing. However, we know little about age-related… J Exp Biol vol. 223, , jeb235002
ISSN
1477-9145
https://dx.doi.org/10.1242/jeb.235002
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