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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Nashed Salomé, Louis Emeric, Buisine Nicolas & Sachs Laurent M., May 2026 — Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown. Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches… Developmental Biology vol. 533, , p. 181-188
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.013
Bichon Bérénice, Alfama Gladys, Gaillard Anne-Laure, Quan Feng B., Sourdaine Pascal & Tostivint Hervé, January 2026 — Characterization and expression of urotensin1 and urotensin2 genes in the caudal neurosecretory system of the small-spotted catshark Scyliorhinus canicula. The caudal neurosecretory system (CNSS) is a neuroendocrine complex unique to fish. In teleosts, the neuroendocrine neurons of… General and Comparative Endocrinology vol. 376, , p. 114866
ISSN
1095-6840
https://dx.doi.org/10.1016/j.ygcen.2025.114866
Ardenkjær-Skinnerup Jacob, Baert Yoni, Bajard Lola, Blum Jonathan, Brion François, Coppola Lucia, Fini Jean-Baptiste, Fritsche Ellen, Holbech Henrik, Hurem Selma, Jacobs Miriam Naomi, Johansson Hanna Katarina Lilith, Knapen Dries, Koch Katharina, Lyche Jan Ludvig et al., 2026 — New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project. Endocrine disruptors (EDs) are implicated in adverse developmental and reproductive outcomes, yet their identification remains… Frontiers in Toxicology vol. 8, , p. 1736963
ISSN
2673-3080
https://dx.doi.org/10.3389/ftox.2026.1736963
Elagali Ahmed, Rüegg Joëlle, Caporale Nicolò, Testa Giuseppe, Sapounidou Maria, Fini Jean-Baptiste, Andersson Patrik L., Dunlop Sarah, Bornehag Carl-Gustaf & Gennings Chris, March 2026 — From correlation to causation: Integrating cohorts with experimental studies in mixture toxicology. Harmful chemical mixtures are pervasive in the environment, yet traditional epidemiological designs face major challenges in… Neurotoxicology vol. 113, , p. 103399
ISSN
1872-9711
https://dx.doi.org/10.1016/j.neuro.2026.103399
Louis Emeric M., Fu Liezhen, Luu Nga, Sachs Laurent M. & Shi Yun-Bo, March 2026 — Protocol for streamlining genotyping of germline-transmissible mutants from genome editing by using a parallel qPCR-based index and R analysis. Targeted genome editing using CRISPR-Cas, ZFNs, or TALENs enables precise gene function studies but often produces point… STAR protocols vol. 7, n° 2, p. 104454
ISSN
2666-1667
https://dx.doi.org/10.1016/j.xpro.2026.104454
Louis Emeric M., Luu Nga, Sachs Laurent M. & Shi Yun-Bo, March 2026 — The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such… Cell & Bioscience vol. 16, n° 1, p. 26
ISSN
2045-3701
https://dx.doi.org/10.1186/s13578-026-01537-8
Grimaldi Alexis, Rigolet Muriel, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., May 2026 — Crosstalk between corticosterone and triiodothyronine signaling in Xenopus tropicalis hindlimb buds. Thyroid hormone signaling has a wide range of biological effects involved in the control of homeostasis and development. In… Developmental Biology vol. 533, , p. 1-15
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.001
Babajko S, Buz M, Finie JB & Den Besten P, April 2026 — Water Fluoridation Risks or Benefits: Summary of the Symposium Presented During the Enamel 11 Meeting Held in Paris France. Calcified Tissue International vol. 117, n° 1, p. 57
ISSN
1432-0827
https://dx.doi.org/10.1007/s00223-026-01525-7
Butruille L., Guittonneau C., Le Blay K., Valcarcel V., Aigrot M. S., Fini J. B., Zalc B. & Remaud S., July 2026 — Early-life PFOS exposure causes lasting impairment of neural stem cell fate, white matter maturation, and olfactory behavior. Per- and polyfluoroalkyl substances (PFAS) are widespread and persistent environmental pollutants that bioaccumulate and are… Ecotoxicol Environ Saf vol. 320, , p. 120365
ISSN
1090-2414
https://dx.doi.org/10.1016/j.ecoenv.2026.120365
Herranen Anni, Rannaud-Bartaire Patricia, Escoube Raphaëlle, Manoury Annabelle, Bouvier-Capely Céline & Fini Jean-Baptiste, January 2026 — A pilot study to develop a murine model of iodine deficiency using sodium perchlorate exposure. Abstract Objective Moderate iodine deficiency is common worldwide and its health consequences are not fully understood. To… Environmental Endocrinology vol. 2, n° 1, wkag004
ISSN
3049-7442
https://dx.doi.org/10.1093/enendo/wkag004
Rannaud-Bartaire Patricia, Herranen Anni, Levi Giovanni, Demeneix Barbara & Fini Jean-Baptiste, March 2026 — Environmental challenges to thyroid homeostasis: Combined effects of iodine deficiency and endocrine disruption. Current Opinion in Endocrine and Metabolic Research vol. 42, , p. 100597
ISSN
24519650
https://dx.doi.org/10.1016/j.coemr.2026.100597
Samee Nadeem, Belz Lou, Narboux-Nême Nicolas, Roux Jean-Christophe, Panayotis Nicolas & Levi Giovanni, May 2026 — Increased Osteoclast Activity Contributes to Bone Resorption and Osteopenia in a Rett Syndrome Mouse Model. Rett syndrome is a severe neurodevelopmental disorder caused predominantly by loss-of-function mutations in the X-linked gene… Cells vol. 15, n° 10, p. 948
ISSN
2073-4409
https://dx.doi.org/10.3390/cells15100948
Nashed Salomé, Uguen Patricia, Sachs Laurent M. & Buisine Nicolas, June 2026 — VIJB: a companion of the JBROWSE genome browser for the visually impaired people. MOTIVATION: The availability of touch-sensitive and haptic devices has been a keystone development for the inclusion of… Bioinformatics , , btag396
ISSN
1367-4811
https://dx.doi.org/10.1093/bioinformatics/btag396
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By authors

  • Gladys ALFAMA
  • Lou BELZ
  • Bérénice BICHON
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Barbara DEMENEIX
  • Jean-Baptiste FINI
  • Anne-Laure GAILLARD
  • Clélia GUITTONNEAU
  • Anni HERRANEN
  • Karine LE BLAY
  • Giovanni LEVI
  • Emeric LOUIS
  • Nicolas NARBOUX-NÊME
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Laurent SACHS
  • Hervé TOSTIVINT

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  • (-) 2026

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  • BBC
  • DESYNE
  • RODEO

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  • MNHN

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