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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Diaz Silvina Laura, Narboux-Nême Nicolas, Boutourlinsky Katia, Doly Stéphane & Maroteaux Luc, February 2016 — Mice lacking the serotonin 5-HT2B receptor as an animal model of resistance to selective serotonin reuptake inhibitors antidepressants. Eur Neuropsychopharmacol vol. 26, n° 2, p. 265-279
ISSN
1873-7862
https://dx.doi.org/10.1016/j.euroneuro.2015.12.012
Bellessort Brice, Le Cardinal Marine, Bachelot Anne, Narboux-Nême Nicolas, Garagnani Paolo, Pirazzini Chiara, Barbieri Ottavia, Mastracci Luca, Jonchere Vincent, Duvernois-Berthet Evelyne, Fontaine Anastasia, Alfama Gladys & Levi Giovanni, January 2016 — Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis. Hum. Mol. Genet. vol. 25, n° 1, p. 97-108
ISSN
1460-2083
https://dx.doi.org/10.1093/hmg/ddv452
Kitazawa Taro, Takechi Masaki, Hirasawa Tatsuya, Adachi Noritaka, Narboux-Nême Nicolas, Kume Hideaki, Maeda Kazuhiro, Hirai Tamami, Miyagawa-Tomita Sachiko, Kurihara Yukiko, Hitomi Jiro, Levi Giovanni, Kuratani Shigeru & Kurihara Hiroki, April 2015 — Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids. Nat Commun vol. 6, , p. 6853
ISSN
2041-1723
https://dx.doi.org/10.1038/ncomms7853
Gaspar Patricia, Nicol Xavier, Narboux-Nême Nicolas & Rebsam Alexandra, 2015 — [Contribution of synaptic release mechanisms to the building of sensory maps]. Biol Aujourdhui vol. 209, n° 1, p. 87-95
ISSN
2105-0686
https://dx.doi.org/10.1051/jbio/2015007
Heude Églantine, Bellessort Brice, Fontaine Anastasia, Hamazaki Manatsu, Treier Anna-Corina, Treier Mathias, Levi Giovanni & Narboux-Nême Nicolas, March 2015 — Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome. Hum. Mol. Genet. vol. 24, n° 6, p. 1670-1681
ISSN
1460-2083
https://dx.doi.org/10.1093/hmg/ddu579
Préau Laetitia, Fini Jean Baptiste, Morvan-Dubois Ghislaine & Demeneix Barbara, February 2015 — Thyroid hormone signaling during early neurogenesis and its significance as a vulnerable window for endocrine disruption. Biochim. Biophys. Acta vol. 1849, n° 2, p. 112-121
ISSN
0006-3002
https://dx.doi.org/10.1016/j.bbagrm.2014.06.015
Punzon I., Latapie V., Le Mével S., Hagneau A., Jolivet P., Palmier K., Fini J. B. & Demeneix B. A., July 2013 — Towards a humanized PPARγ reporter system for in vivo screening of obesogens. Mol. Cell. Endocrinol. vol. 374, 1-2, p. 1-9
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2013.04.004
Morvan-Dubois G., Fini J. B. & Demeneix B. A., 2013 — Is thyroid hormone signaling relevant for vertebrate embryogenesis?. Curr. Top. Dev. Biol. vol. 103, , p. 365-396
ISSN
1557-8933
https://dx.doi.org/10.1016/B978-0-12-385979-2.00013-7
Fini Jean-Baptiste, Riu Anne, Debrauwer Laurent, Hillenweck Anne, Le Mével Sébastien, Chevolleau Sylvie, Boulahtouf Abdelaye, Palmier Karima, Balaguer Patrick, Cravedi Jean-Pierre, Demeneix Barbara A. & Zalko Daniel, February 2012 — Parallel biotransformation of tetrabromobisphenol A in Xenopus laevis and mammals: Xenopus as a model for endocrine perturbation studies. Toxicol. Sci. vol. 125, n° 2, p. 359-367
ISSN
1096-0929
https://dx.doi.org/10.1093/toxsci/kfr312
Dupré Sandrine M., Guissouma Hajer, Flamant Frédéric, Seugnet Isabelle, Scanlan Thomas S., Baxter John D., Samarut Jacques, Demeneix Barbara A. & Becker Nathalie, May 2004 — Both thyroid hormone receptor (TR)beta 1 and TR beta 2 isoforms contribute to the regulation of hypothalamic thyrotropin-releasing hormone. Endocrinology vol. 145, n° 5, p. 2337-2345
ISSN
0013-7227
https://dx.doi.org/10.1210/en.2003-1209
Safi Rachid, Bertrand Stéphanie, Marchand Oriane, Duffraisse Marilyne, de Luze Amaury, Vanacker Jean-Marc, Maraninchi Marie, Margotat Alain, Demeneix Barbara & Laudet Vincent, February 2004 — The axolotl (Ambystoma mexicanum), a neotenic amphibian, expresses functional thyroid hormone receptors. Endocrinology vol. 145, n° 2, p. 760-772
ISSN
0013-7227
https://dx.doi.org/10.1210/en.2003-0913
Demeneix Barbara, Vandenberg Laura N., Ivell Richard & Zoeller R. Thomas, October 2020 — Thresholds and Endocrine Disruptors: An Endocrine Society Policy Perspective. The concept of a threshold of adversity in toxicology is neither provable nor disprovable. As such, it is not a scientific… J Endocr Soc . vol. 4, n° 10, bvaa085
ISSN
2472-1972
https://dx.doi.org/10.1210/jendso/bvaa085
Landrigan Philip J., Stegeman John J., Fleming Lora E., Allemand Denis, Anderson Donald M., Backer Lorraine C., Brucker-Davis Françoise, Chevalier Nicolas, Corra Lilian, Czerucka Dorota, Bottein Marie-Yasmine Dechraoui, Demeneix Barbara, Depledge Michael, Deheyn Dimitri D., Dorman CharlesJ. et al., 2020 — Human Health and Ocean Pollution. Background: Pollution - unwanted waste released to air, water, and land by human activity - is the largest environmental cause… Ann Glob Health vol. 86, n° 1, p. 151
ISSN
2214-9996
https://dx.doi.org/10.5334/aogh.2831
Gardos G. & Cole J. O., — Maintenance antipsychotic therapy: is the cure worse than the disease?. The serious long-term complications of maintenance antipsychotic therapy led the authors to undertake a critical review of… vol. 133, n° 1, p. 32-36
ISSN
0002-953X
https://dx.doi.org/10.1176/ajp.133.1.32
Delfosse Vanessa, Huet Tiphaine, Harrus Deborah, Granell Meritxell, Bourguet Maxime, Gardia-Parège Caroline, Chiavarina Barbara, Grimaldi Marina, Le Mével Sébastien, Blanc Pauline, Huang David, Gruszczyk Jakub, Demeneix Barbara, Cianférani Sarah, Fini Jean-Baptiste et al., 2021 — Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Humans are chronically exposed to mixtures of xenobiotics referred to as endocrine-disrupting chemicals (EDCs). A vast body of… Proc Natl Acad Sci USA vol. 118, n° 1, e2020551118
ISSN
1091-6490
https://dx.doi.org/10.1073/pnas.2020551118
Lupu Diana, Andersson Patrik, Bornehag Carl-Gustaf, Demeneix Barbara, Fritsche Ellen, Gennings Chris, Lichtensteiger Walter, Leist Marcel, Leonards Pim E. G., Ponsonby Anne-Louise, Scholze Martin, Testa Giuseppe, Tresguerres Jesus A. F., Westerink Remco H. S., Zalc Bernard et al., June 2020 — The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity. Ubiquitous exposure to endocrine-disrupting chemicals (EDCs) has caused serious concerns about the ability of these chemicals… Int J Mol Sci vol. 21, n° 11, p. 3978
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms21113978
Krief Sabrina, Iglesias-González Alba, Appenzeller Brice MarcRené, Okimat John Paul, Fini Jean-Baptiste, Demeneix Barbara, Vaslin-Reimann Sophie, Lardy-Fontan Sophie, Guma Nelson & Spirhanzlova Petra, May 2020 — Road impact in a protected area with rich biodiversity: the case of the Sebitoli road in Kibale National Park, Uganda. While road network expansion is crucial for economic development, it can cause a notable disturbance of fauna, especially in… Environ Sci Pollut Res Int vol. 27, n° 22, p. 27914-27925
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-020-09098-0
Kortenkamp Andreas, Axelstad Marta, Baig Asma H., Bergman Åke, Bornehag Carl-Gustaf, Cenijn Peter, Christiansen Sofie, Demeneix Barbara, Derakhshan Arash, Fini Jean-Baptiste, Frädrich Caroline, Hamers Timo, Hellwig Lina, Köhrle Josef, Korevaar Tim I. M. et al., 2020 — Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals-The ATHENA Project. The test methods that currently exist for the identification of thyroid hormone system-disrupting chemicals are woefully… Int J Mol Sci vol. 21, n° 9, E3123
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms21093123
Demeneix Barbara A., December 2019 — Evidence for Prenatal Exposure to Thyroid Disruptors and Adverse Effects on Brain Development. Thyroid hormone regulates vital processes in early brain development such as neuronal stem cell proliferation, migration, and… Eur Thyroid J vol. 8, n° 6, p. 283-292
ISSN
2235-0640
https://dx.doi.org/10.1159/000504668
Leemans Michelle, Couderq Stephan, Demeneix Barbara & Fini Jean-Baptiste, 2019 — Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data. Plant Protection Products, more commonly referred to as pesticides and biocides, are used to control a wide range of yield… Front Endocrinol (Lausanne) vol. 10, , p. 743
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2019.00743
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