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PhyMA est une Unité Mixte de Recherche CNRS-MNHN (UMR 7221).
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Physiologie moléculaire et adaptation
UMR 7221

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Favreau Charly, Tribondeau Alicia, Marugan Marie, Guyot François, Alpha-Bazin Beatrice, Marie Arul, Puppo Remy, Dufour Thierry, Huguet Arnaud, Zirah Séverine & Kish Adrienne, 2022 — Molecular acclimation of Halobacterium salinarum to halite brine inclusions. Halophilic microorganisms have long been known to survive within the brine inclusions of salt crystals, as evidenced by the… Front Microbiol . vol. 13, , p. 1075274
ISSN
1664-302X
https://dx.doi.org/10.3389/fmicb.2022.1075274
Vancamp Pieter, Spirhanzlova Petra, Sébillot Anthony, Butruille Lucile, Gothié Jean-David, Le Mével Sébastien, Leemans Michelle, Wejaphikul Karn, Meima Marcel, Mughal Bilal B., Roques Pierre, Remaud Sylvie, Fini Jean-Baptiste & Demeneix Barbara A., 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2021.117654
Messina Simone, Edwards David Paul, Van Houtte Natalie, Tomassi Suzanne, Benedick Suzan, Eens Marcel & Costantini David, 2021 — Impacts of selective logging on haemosporidian infection and physiological correlates in tropical birds. Tropical forest degradation affects host-parasite interactions, determining the probability of animals acquiring an infection… Int J Parasitol. , , S0020–7519(21)00259–9
ISSN
1879-0135
https://dx.doi.org/10.1016/j.ijpara.2021.07.003
Toussaint-Lardé Isabelle, Louppe Vivien, Sanchez-Garrido Frida, Taillades Morgane, Amine Ryadh, Mandica Mark, Heude Eglantine, Herrel Anthony & Fabre Anne-Claire, juillet 2025 — The impact of size and ontogeny on suction feeding kinematics in the axolotl (Ambystoma mexicanum). Size impacts all aspects of life in animals. Not only does it impact metabolism and physiology, it also affects movements,… Biology Open vol. 14, n° 7, bio061860
ISSN
2046-6390
https://dx.doi.org/10.1242/bio.061860
Goutte Aurélie, Martin Nicolas, Alliot Fabrice, Angelier Frédéric, Blanchouin Arnaud, Costantini David, Lesimple Maxime, Ribout Cécile, Traoré Sira, Villalta Rémi & Blanchoud Hélène, décembre 2024 — From cells to recapture rates: responses and recovery of a wild fish after an experimental exposure to a widely used herbicide. Environmental Science and Pollution Research , ,
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-024-35837-8
Dufour Sylvie, Sachs Laurent, Martin Patrick & Rousseau Karine, 2025 — [Metamorphoses in fishes and their endocrine regulations]. The most emblematic metamorphoses in the animal kingdom remain those of the caterpillar into a butterfly and the tadpole into a… Biologie Aujourd'hui vol. 219, n° 1, p. 37-50
ISSN
2105-0686
https://dx.doi.org/10.1051/jbio/2025002
Nashed Salomé, Louis Emeric, Buisine Nicolas & Sachs Laurent M., mai 2026 — Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown. Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches… Developmental Biology vol. 533, , p. 181-188
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.013
Bichon Bérénice, Alfama Gladys, Gaillard Anne-Laure, Quan Feng B., Sourdaine Pascal & Tostivint Hervé, janvier 2026 — Characterization and expression of urotensin1 and urotensin2 genes in the caudal neurosecretory system of the small-spotted catshark Scyliorhinus canicula. The caudal neurosecretory system (CNSS) is a neuroendocrine complex unique to fish. In teleosts, the neuroendocrine neurons of… General and Comparative Endocrinology vol. 376, , p. 114866
ISSN
1095-6840
https://dx.doi.org/10.1016/j.ygcen.2025.114866
Bichon Bérénice, Alfama Gladys, Gaillard Anne-Laure, Tostivint Hervé & Pézeron Guillaume, septembre 2025 — Impact of acute environmental challenges on the expression of peptide hormone-encoding genes in the zebrafish caudal neurosecretory system. The caudal neurosecretory system (CNSS) is a neuroendocrine complex unique to fish, first described in 1955. Since then, it has… Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology vol. 307, , p. 111893
ISSN
1531-4332
https://dx.doi.org/10.1016/j.cbpa.2025.111893
Valcarcel-Hernandez V., Butruille L. & Remaud S., décembre 2025 — Effects of thyroid disruption on neural cells stem fate in the mouse brain. Thyroid hormones (THs), particularly T3 and T4, play crucial roles in neural development and maintenance by regulating neural… Presse Medicale vol. 54, n° 4, p. 104312
ISSN
2213-0276
https://dx.doi.org/10.1016/j.lpm.2025.104312
Ardenkjær-Skinnerup Jacob, Baert Yoni, Bajard Lola, Blum Jonathan, Brion François, Coppola Lucia, Fini Jean-Baptiste, Fritsche Ellen, Holbech Henrik, Hurem Selma, Jacobs Miriam Naomi, Johansson Hanna Katarina Lilith, Knapen Dries, Koch Katharina, Lyche Jan Ludvig et al., 2026 — New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project. Endocrine disruptors (EDs) are implicated in adverse developmental and reproductive outcomes, yet their identification remains… Frontiers in Toxicology vol. 8, , p. 1736963
ISSN
2673-3080
https://dx.doi.org/10.3389/ftox.2026.1736963
Elagali Ahmed, Rüegg Joëlle, Caporale Nicolò, Testa Giuseppe, Sapounidou Maria, Fini Jean-Baptiste, Andersson Patrik L., Dunlop Sarah, Bornehag Carl-Gustaf & Gennings Chris, mars 2026 — From correlation to causation: Integrating cohorts with experimental studies in mixture toxicology. Harmful chemical mixtures are pervasive in the environment, yet traditional epidemiological designs face major challenges in… Neurotoxicology vol. 113, , p. 103399
ISSN
1872-9711
https://dx.doi.org/10.1016/j.neuro.2026.103399
European Food Safety Authority (EFSA) and Baumann Lisa, Baynes Alice, Bennekou Susanne Hougaard, Crofton Kevin, Dang Zhichao, Degitz Sigmund, Fini Jean-Baptiste, Gilbert Mary, Holbech Henrik, Terron Andrea, Van Duursen Majorie, McVey Emily, Arena Maria, Kienzler Aude, Rizzuto Simone et al., décembre 2025 — The assessment for potential thyroid-mediated endocrine disruption in amphibians: Clarification on the use of new methods and on the interpretation of changes in thyroid histology. Amphibians (specifically Xenopus laevis) are used as the model species to assess potential endocrine-disrupting properties in… EFSA journal. European Food Safety Authority vol. 23, n° 12, e9815
ISSN
1831-4732
https://dx.doi.org/10.2903/j.efsa.2025.9815
Herranen Anni, Rannaud-Bartaire Patricia & Fini Jean-Baptiste, juin 2025 — The thyroid hormone system and its disruption. Annales D’endocrinologie vol. 86, n° 3, p. 101773
ISSN
2213-3941
https://dx.doi.org/10.1016/j.ando.2025.101773
Krief Sabrina, Spirhanzlova Petra & Fini Jean-Baptiste, juin 2025 — Crisis on the Planet of the Apes-Plastic, the new threat?. INTRODUCTION: Chimpanzees, our closest relatives, are threatened with extinction by poaching, zoonoses, fragmentation and the… Annales D’endocrinologie vol. 86, n° 3, p. 101778
ISSN
2213-3941
https://dx.doi.org/10.1016/j.ando.2025.101778
Ullrich Simon, Leidescher Susanne, Feodorova Yana, Thanisch Katharina, Fini Jean-Baptiste, Kaspers Bernd, Weber Frank, Markova Boyka, Führer Dagmar, Romitti Mirian, Krebs Stefan, Blum Helmut, Leonhardt Heinrich, Costagliola Sabine, Heuer Heike et al., 2025 — Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes. [This corrects the article DOI: 10.3389/fcell.2023.1265407.]. Frontiers in Cell and Developmental Biology vol. 13, , p. 1571466
ISSN
2296-634X
https://dx.doi.org/10.3389/fcell.2025.1571466
Fénichel Patrick, Todaka Emiko, Etzel Ruth A., Chan Chang-Chuan, Barouki Robert, Chevalier Nicolas, Fini Jean-Baptiste, Poore Kirsten R., Sakabe Kou, Siroux Valerie, Yamamoto Midori & Mori Chisato, 2024 — Call to introduce environmental preventive medicine courses to the medical curriculum. An initial experience of an education program at the Faculty of Medicine of Nice, University of Côte d’Azur. Frontiers in Medicine vol. 11, , p. 1412674
ISSN
2296-858X
https://dx.doi.org/10.3389/fmed.2024.1412674
Louis Emeric M., Fu Liezhen, Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — Protocol for streamlining genotyping of germline-transmissible mutants from genome editing by using a parallel qPCR-based index and R analysis. Targeted genome editing using CRISPR-Cas, ZFNs, or TALENs enables precise gene function studies but often produces point… STAR protocols vol. 7, n° 2, p. 104454
ISSN
2666-1667
https://dx.doi.org/10.1016/j.xpro.2026.104454
Louis Emeric M., Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such… Cell & Bioscience vol. 16, n° 1, p. 26
ISSN
2045-3701
https://dx.doi.org/10.1186/s13578-026-01537-8
Grimaldi Alexis, Rigolet Muriel, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mai 2026 — Crosstalk between corticosterone and triiodothyronine signaling in Xenopus tropicalis hindlimb buds. Thyroid hormone signaling has a wide range of biological effects involved in the control of homeostasis and development. In… Developmental Biology vol. 533, , p. 1-15
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.001
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