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PhyMA est une Unité Mixte de Recherche CNRS-MNHN (UMR 7221).
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Physiologie moléculaire et adaptation
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Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, septembre 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
ISSN
1879-1514
https://dx.doi.org/10.1016/j.aquatox.2024.107081
Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, juin 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2024.108861
Tribondeau Alicia, Du Pasquier David, Benchouaia Médine, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mars 2024 — Overlapping action of T3 and T4 during Xenopus laevis development. Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However,… Frontiers in Endocrinology vol. 15, , p. 1360188
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2024.1360188
Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., janvier 2024 — Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-023-43012-9
Pesce Elise, Garde Marion, Rigolet Muriel, Tindall Andrew J., Lemkine Gregory F., Baumann Lisa A., Sachs Laurent M. & Du Pasquier David, décembre 2023 — A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka. Identifying endocrine disrupting chemicals in order to limit their usage is a priority and required according to the European… Environ. Sci. Technol. , ,
ISSN
1520-5851
https://dx.doi.org/10.1021/acs.est.3c05515
Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023 — Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2023.1208182
Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
ISSN
1664-8021
https://dx.doi.org/10.3389/fgene.2022.996826
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
ISSN
1097-0177
https://dx.doi.org/10.1002/dvdy.304
Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two… Cells vol. 10, n° 9, p. 2375
ISSN
2073-4409
https://dx.doi.org/10.3390/cells10092375
Vancamp Pieter, Spirhanzlova Petra, Sébillot Anthony, Butruille Lucile, Gothié Jean-David, Le Mével Sébastien, Leemans Michelle, Wejaphikul Karn, Meima Marcel, Mughal Bilal B., Roques Pierre, Remaud Sylvie, Fini Jean-Baptiste & Demeneix Barbara A., 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2021.117654
Kyono Yasuhiro, Raj Samhitha, Sifuentes Christopher J., Buisine Nicolas, Sachs Laurent & Denver Robert J., mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial… Dev. Biol. , ,
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2020.03.013
Terrien Jérémy, Seugnet Isabelle, Seffou Bolaji, Herrero Maria J., Bowers James, Chamas Lamis, Decherf Stéphanie, Duvernois-Berthet Evelyne, Djediat Chakib, Ducos Bertrand, Demeneix Barbara A. & Clerget-Froidevaux Marie-Stéphanie, décembre 2019 — Reduced central and peripheral inflammatory responses and increased mitochondrial activity contribute to diet-induced obesity resistance in WSB/EiJ mice. Sci Rep vol. 9, n° 1, p. 19696
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-019-56051-4
Kerdivel Gwenneg, Blugeon Corinne, Fund Cédric, Rigolet Muriel, Sachs Laurent M. & Buisine Nicolas, 2019 — Opposite T3 Response of ACTG1-FOS Subnetwork Differentiate Tailfin Fate in Xenopus Tadpole and Post-hatching Axolotl. Front Endocrinol (Lausanne) vol. 10, , p. 194
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2019.00194
Buisine Nicolas, Ruan Xiaoan, Ruan Yijun & Sachs Laurent M., août 2018 — Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues. Cold Spring Harb Protoc vol. 2018, n° 8, pdb.prot104620
ISSN
1559-6095
https://dx.doi.org/10.1101/pdb.prot104620
Buisine Nicolas, Ruan Xiaoan, Ruan Yijun & Sachs Laurent M., août 2018 — Chromatin Immunoprecipitation for Chromatin Interaction Analysis Using Paired-End-Tag (ChIA-PET) Sequencing in Tadpole Tissues. Cold Spring Harb Protoc vol. 2018, n° 8, pdb.prot097725
ISSN
1559-6095
https://dx.doi.org/10.1101/pdb.prot097725
Bellessort Brice, Bachelot Anne, Grouthier Virginie, DeLombares Camille, Narboux-Neme Nicolas, Garagnani Paolo, Pirazzini Chiara, Astigiano Simonetta, Mastracci Luca, Fontaine Anastasia, Alfama Gladys, Duvernois-Berthet Evelyne & Levi Giovanni, 2018 — Comparative analysis of molecular signatures suggests the use of gabapentin for the management of endometriosis-associated pain. J Pain Res vol. 11, , p. 715-725
ISSN
1178-7090
https://dx.doi.org/10.2147/JPR.S163611
Buisine Nicolas, Kerdivel Gwenneg & Sachs Laurent M., 2018 — De Novo Transcriptomic Approach to Study Thyroid Hormone Receptor Action in Non-mammalian Models. Methods Mol. Biol. vol. 1801, , p. 265-285
ISSN
1940-6029
https://dx.doi.org/10.1007/978-1-4939-7902-8_21
Schneider Katelin A., Shewade Leena H., Buisine Nicolas, Sachs Laurent M. & Buchholz Daniel R., 2018 — A novel stress hormone response gene in tadpoles of Xenopus tropicalis. Gen. Comp. Endocrinol. vol. 260, , p. 107-114
ISSN
1095-6840
https://dx.doi.org/10.1016/j.ygcen.2018.01.006
Olvera A., Martyniuk C. J., Buisine N., Jiménez-Jacinto V., Sanchez-Flores A., Sachs L. M. & Orozco A., novembre 2017 — Differential transcriptome regulation by 3,5-T2 and 3’,3,5-T3 in brain and liver uncovers novel roles for thyroid hormones in tilapia. Sci Rep vol. 7, n° 1, p. 15043
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-017-14913-9
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  • Gladys ALFAMA
  • Anne BACHELOT
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • Barbara DEMENEIX
  • Evelyne DUVERNOIS-BERTHET
  • Jean-Baptiste FINI
  • Anastasia FONTAINE
  • Fabrice GIRARDOT
  • Karine LE BLAY
  • Sébastien LE MEVEL
  • Giovanni LEVI
  • Nicolas NARBOUX-NÊME
  • Elise PESCE
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Laurent SACHS
  • Isabelle SEUGNET
  • Alicia TRIBONDEAU
  • Pieter VANCAMP

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