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PhyMA est une Unité Mixte de Recherche CNRS-MNHN (UMR 7221).
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Physiologie moléculaire et adaptation
UMR 7221

Recherche

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Kyono Yasuhiro, Raj Samhitha, Sifuentes Christopher J., Buisine Nicolas, Sachs Laurent & Denver Robert J., mars 2020 — DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain. Methylation of cytosine residues in DNA influences chromatin structure and gene transcription, and its regulation is crucial… Dev. Biol. , ,
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2020.03.013
Fini Jean-Baptiste, mai 2019 — Mixtures measured in human, disrupt thyroid hormone signaling and behavior in Xenopus laevis. EJEA , ,
ISSN
1479-6848
https://dx.doi.org/10.1530/endoabs.63.S7.1
Vaudry Hubert, Leprince Jérôme, Chatenet David, Fournier Alain, Lambert David G., Le Mével Jean-Claude, Ohlstein Eliot H., Schwertani Adel, Tostivint Hervé & Vaudry David, 2015 — International Union of Basic and Clinical Pharmacology. XCII. Urotensin II, urotensin II-related peptide, and their receptor: from structure to function. Urotensin II (UII) is a cyclic neuropeptide that was first isolated from the urophysis of teleost fish on the basis of its… Pharmacol Rev vol. 67, n° 1, p. 214-258
ISSN
1521-0081
https://dx.doi.org/10.1124/pr.114.009480
Djenoune Lydia, Khabou Hanen, Joubert Fanny, Quan Feng B., Nunes Figueiredo Sophie, Bodineau Laurence, Del Bene Filippo, Burcklé Céline, Tostivint Hervé & Wyart Claire, 2014 — Investigation of spinal cerebrospinal fluid-contacting neurons expressing PKD2L1: evidence for a conserved system from fish to primates. Over 90 years ago, Kolmer and Agduhr identified spinal cerebrospinal fluid-contacting neurons (CSF-cNs) based on their… Front Neuroanat vol. 8, , p. 26
ISSN
1662-5129
https://dx.doi.org/10.3389/fnana.2014.00026
Rodríguez-Carrillo Andrea, Rosenmai Anna Kjerstine, Mustieles Vicente, Couderq Stephan, Fini Jean-Baptiste, Vela-Soria Fernando, Molina-Molina Jose Manuel, Ferrando-Marco Patricia, Wielsøe Maria, Long Manhai, Bonefeld-Jorgensen Eva Cecilie, Olea Nicolás, Vinggaard Anne Marie & Fernández Mariana F., janvier 2021 — Assessment of chemical mixtures using biomarkers of combined biological activity: A screening study in human placentas. Reproductive Toxicology , , S0890623821000022
ISSN
08906238
https://dx.doi.org/10.1016/j.reprotox.2021.01.002
Nguyen Duy, Buisine Nicolas, Fayol Olivier, Michels Annemieke A., Bensaude Olivier, Price David H. & Uguen Patricia, août 2021 — An alternative D. melanogaster 7SK snRNP. BACKGROUND: The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA… BMC Mol Cell Biol vol. 22, n° 1, p. 43
ISSN
2661-8850
https://dx.doi.org/10.1186/s12860-021-00381-7
Thambirajah Anita A., Wade Michael G., Verreault Jonathan, Buisine Nicolas, Alves Verônica A., Langlois Valerie S. & Helbing Caren C., août 2021 — Disruption by stealth - Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals. Thyroid hormones (THs) are important regulators of growth, development, and homeostasis of all vertebrates. There are many… Environ Res vol. 203, , p. 111906
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2021.111906
Antoine-Lorquin Aymeric, Arensburger Peter, Arnaoty Ahmed, Asgari Sassan, Batailler Martine, Beauclair Linda, Belleannée Catherine, Buisine Nicolas, Coustham Vincent, Guyetant Serge, Helou Laura, Lecomte Thierry, Pitard Bruno, Stévant Isabelle & Bigot Yves, mai 2021 — Two repeated motifs enriched within some enhancers and origins of replication are bound by SETMAR isoforms in human colon cells. Setmar is a gene specific to simian genomes. The function(s) of its isoforms are poorly understood and their existence in… Genomics vol. 113, n° 3, p. 1589-1604
ISSN
1089-8646
https://dx.doi.org/10.1016/j.ygeno.2021.03.032
Helou Laura, Beauclair Linda, Dardente Hugues, Arensburger Peter, Buisine Nicolas, Jaszczyszyn Yan, Guillou Florian, Lecomte Thierry, Kentsis Alex & Bigot Yves, avril 2021 — The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition. PiggyBac(PB)-like elements (pble) are members of a eukaryotic DNA transposon family. This family is of interest to evolutionary… J Mol Biol vol. 433, n° 7, p. 166805
ISSN
1089-8638
https://dx.doi.org/10.1016/j.jmb.2020.166805
Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021 — Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two… Cells vol. 10, n° 9, p. 2375
ISSN
2073-4409
https://dx.doi.org/10.3390/cells10092375
Nguyen Duy, Fayol Olivier, Buisine Nicolas, Lecorre Pierrette & Uguen Patricia, 2016 — Functional Interaction between HEXIM and Hedgehog Signaling during Drosophila Wing Development. Studying the dynamic of gene regulatory networks is essential in order to understand the specific signals and factors that… PLoS One vol. 11, n° 5, e0155438
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0155438
Vancamp Pieter, Spirhanzlova Petra, Sébillot Anthony, Butruille Lucile, Gothié Jean-David, Le Mével Sébastien, Leemans Michelle, Wejaphikul Karn, Meima Marcel, Mughal Bilal B., Roques Pierre, Remaud Sylvie, Fini Jean-Baptiste & Demeneix Barbara A., 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2021.117654
Messina Simone, Edwards David Paul, Van Houtte Natalie, Tomassi Suzanne, Benedick Suzan, Eens Marcel & Costantini David, 2021 — Impacts of selective logging on haemosporidian infection and physiological correlates in tropical birds. Tropical forest degradation affects host-parasite interactions, determining the probability of animals acquiring an infection… Int J Parasitol. , , S0020–7519(21)00259–9
ISSN
1879-0135
https://dx.doi.org/10.1016/j.ijpara.2021.07.003
Cheron Marion, Costantini David, Angelier Frédéric, Ribout Cécile & Brischoux François, 2021 — Aminomethylphosphonic acid (AMPA) alters oxidative status during embryonic development in an amphibian species. Glyphosate’s primary metabolite (aminomethylphosphonic acid, AMPA) is known to alter embryonic development at environmentally… Chemosphere vol. 287, , p. 131882
ISSN
1879-1298
https://dx.doi.org/10.1016/j.chemosphere.2021.131882
Ohmer Michel E. B., Costantini David, Czirják Gábor Á, Downs Cynthia J., Ferguson Laura V., Flies Andy, Franklin Craig E., Kayigwe Ahab N., Knutie Sarah, Richards-Zawacki Corinne L. & Cramp Rebecca L., 2021 — Applied ecoimmunology: using immunological tools to improve conservation efforts in a changing world. Ecoimmunology is a rapidly developing field that explores how the environment shapes immune function, which in turn influences… Conserv Physiol. vol. 9, n° 1, coab074
ISSN
2051-1434
https://dx.doi.org/10.1093/conphys/coab074
Derakhshan Arash, Shu Huan, Broeren Maarten A. C., Lindh Christian H., Peeters Robin P., Kortenkamp Andreas, Demeneix Barbara, Bornehag Carl-Gustaf & Korevaar Tim I. M., décembre 2021 — Association of phthalate exposure with thyroid function during pregnancy. BACKGROUND : The extent of thyroid disruptive effects of phthalates during pregnancy remains unclear. AIM: To investigate the… Environ Int. vol. 157, , p. 106795
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2021.106795
Trzaska Carole, Amand Séverine, Bailly Christine, Leroy Catherine, Marchand Virginie, Duvernois-Berthet Evelyne, Saliou Jean-Michel, Benhabiles Hana, Werkmeister Elisabeth, Chassat Thierry, Guilbert Romain, Hannebique David, Mouray Anthony, Copin Marie-Christine, Moreau Pierre-Arthur et al., 2020 — 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nonsense mutations cause about 10\% of genetic disease cases, and no treatments are available. Nonsense mutations can be… Nat Commun. vol. 11, n° 1, p. 1509
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-020-15140-z
Buffet Jean-Philippe, Corre Erwan, Duvernois-Berthet Evelyne, Fournier Jérôme & Lopez Pascal Jean, 2017 — Adhesive gland transcriptomics uncovers a diversity of genes involved in glue formation in marine tube-building polychaetes. Tube-building sabellariid polychaetes are hermatypic organisms capable of forming vast reefs in highly turbulent marine… Acta Biomater. vol. 72, , p. 316-328
ISSN
1878-7568
https://dx.doi.org/10.1016/j.actbio.2018.03.037
Qiao Qin, Le Manach Séverine, Huet Hélène, Duvernois-Berthet Evelyne, Chaouch Soraya, Duval Charlotte, Sotton Benoit, Ponger Loïc, Marie Arul, Mathéron Lucrèce, Lennon Sarah, Bolbach Gérard, Djediat Chakib, Bernard Cécile, Edery Marc et al., 2016 — An integrated omic analysis of hepatic alteration in medaka fish chronically exposed to cyanotoxins with possible mechanisms of reproductive toxicity. Cyanobacterial blooms threaten human health as well as the population of other living organisms in the aquatic environment,… Environ Pollut. vol. 219, , p. 119-131
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2016.10.029
Arivalagan Jaison, Yarra Tejaswi, Marie Benjamin, Sleight Victoria A., Duvernois-Berthet Evelyne, Clark Melody S., Marie Arul & Berland Sophie, 2017 — Insights from the Shell Proteome: Biomineralization to Adaptation. Bivalves have evolved a range of complex shell forming mechanisms that are reflected by their incredible diversity in shell… Sci Rep. vol. 34, n° 1, p. 66-77
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msw219
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  • Gladys ALFAMA
  • Rym AOUCI
  • Anne BACHELOT
  • Lou BELZ
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Mathieu CARRARA
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • David COSTANTINI
  • Stephan COUDERQ
  • Camille DE LOMBARES
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  • Nicolas NARBOUX-NÊME
  • Louise PERICARD
  • Elise PESCE
  • Guillaume PÉZERON
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Karine ROUSSEAU
  • Laurent SACHS
  • Manrico SEBASTIANO
  • Anthony SEBILLOT
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