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PhyMA est une Unité Mixte de Recherche CNRS-MNHN (UMR 7221).
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Butruille L., Guittonneau C., Le Blay K., Valcarcel V., Aigrot M. S., Fini J. B., Zalc B. & Remaud S., juillet 2026 — Early-life PFOS exposure causes lasting impairment of neural stem cell fate, white matter maturation, and olfactory behavior. Per- and polyfluoroalkyl substances (PFAS) are widespread and persistent environmental pollutants that bioaccumulate and are… Ecotoxicol Environ Saf vol. 320, , p. 120365
ISSN
1090-2414
https://dx.doi.org/10.1016/j.ecoenv.2026.120365
Nashed Salomé, Uguen Patricia, Sachs Laurent M. & Buisine Nicolas, juin 2026 — VIJB: a companion of the JBROWSE genome browser for the visually impaired people. MOTIVATION: The availability of touch-sensitive and haptic devices has been a keystone development for the inclusion of… Bioinformatics , , btag396
ISSN
1367-4811
https://dx.doi.org/10.1093/bioinformatics/btag396
Nashed Salomé, Louis Emeric, Buisine Nicolas & Sachs Laurent M., mai 2026 — Molecular and genetic studies on the signaling and the regulation of amphibian metamorphosis by thyroid hormone, the contribution of Jamshed Tata and Donald Brown. Post-embryonic development refers to the process by which embryonic development has been completed and the organism reaches… Developmental Biology vol. 533, , p. 181-188
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.013
Grimaldi Alexis, Rigolet Muriel, Blugeon Corinne, Buisine Nicolas & Sachs Laurent M., mai 2026 — Crosstalk between corticosterone and triiodothyronine signaling in Xenopus tropicalis hindlimb buds. Thyroid hormone signaling has a wide range of biological effects involved in the control of homeostasis and development. In… Developmental Biology vol. 533, , p. 1-15
ISSN
1095-564X
https://dx.doi.org/10.1016/j.ydbio.2026.02.001
Elagali Ahmed, Rüegg Joëlle, Caporale Nicolò, Testa Giuseppe, Sapounidou Maria, Fini Jean-Baptiste, Andersson Patrik L., Dunlop Sarah, Bornehag Carl-Gustaf & Gennings Chris, mars 2026 — From correlation to causation: Integrating cohorts with experimental studies in mixture toxicology. Harmful chemical mixtures are pervasive in the environment, yet traditional epidemiological designs face major challenges in… Neurotoxicology vol. 113, , p. 103399
ISSN
1872-9711
https://dx.doi.org/10.1016/j.neuro.2026.103399
Louis Emeric M., Fu Liezhen, Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — Protocol for streamlining genotyping of germline-transmissible mutants from genome editing by using a parallel qPCR-based index and R analysis. Targeted genome editing using CRISPR-Cas, ZFNs, or TALENs enables precise gene function studies but often produces point… STAR protocols vol. 7, n° 2, p. 104454
ISSN
2666-1667
https://dx.doi.org/10.1016/j.xpro.2026.104454
Louis Emeric M., Luu Nga, Sachs Laurent M. & Shi Yun-Bo, mars 2026 — The methyltransferase activity of Dot1L is essential for Xenopus tropicalis tadpole development and survival. Epigenetic modifications of histones play key roles in transcriptional regulation by diverse transcription factors. One such… Cell & Bioscience vol. 16, n° 1, p. 26
ISSN
2045-3701
https://dx.doi.org/10.1186/s13578-026-01537-8
Rannaud-Bartaire Patricia, Herranen Anni, Levi Giovanni, Demeneix Barbara & Fini Jean-Baptiste, mars 2026 — Environmental challenges to thyroid homeostasis: Combined effects of iodine deficiency and endocrine disruption. Current Opinion in Endocrine and Metabolic Research vol. 42, , p. 100597
ISSN
24519650
https://dx.doi.org/10.1016/j.coemr.2026.100597
Ardenkjær-Skinnerup Jacob, Baert Yoni, Bajard Lola, Blum Jonathan, Brion François, Coppola Lucia, Fini Jean-Baptiste, Fritsche Ellen, Holbech Henrik, Hurem Selma, Jacobs Miriam Naomi, Johansson Hanna Katarina Lilith, Knapen Dries, Koch Katharina, Lyche Jan Ludvig et al., 2026 — New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project. Endocrine disruptors (EDs) are implicated in adverse developmental and reproductive outcomes, yet their identification remains… Frontiers in Toxicology vol. 8, , p. 1736963
ISSN
2673-3080
https://dx.doi.org/10.3389/ftox.2026.1736963
Herranen Anni, Rannaud-Bartaire Patricia, Escoube Raphaëlle, Manoury Annabelle, Bouvier-Capely Céline & Fini Jean-Baptiste, janvier 2026 — A pilot study to develop a murine model of iodine deficiency using sodium perchlorate exposure. Abstract Objective Moderate iodine deficiency is common worldwide and its health consequences are not fully understood. To… Environmental Endocrinology vol. 2, n° 1, wkag004
ISSN
3049-7442
https://dx.doi.org/10.1093/enendo/wkag004
European Food Safety Authority (EFSA) and Baumann Lisa, Baynes Alice, Bennekou Susanne Hougaard, Crofton Kevin, Dang Zhichao, Degitz Sigmund, Fini Jean-Baptiste, Gilbert Mary, Holbech Henrik, Terron Andrea, Van Duursen Majorie, McVey Emily, Arena Maria, Kienzler Aude, Rizzuto Simone et al., décembre 2025 — The assessment for potential thyroid-mediated endocrine disruption in amphibians: Clarification on the use of new methods and on the interpretation of changes in thyroid histology. Amphibians (specifically Xenopus laevis) are used as the model species to assess potential endocrine-disrupting properties in… EFSA journal. European Food Safety Authority vol. 23, n° 12, e9815
ISSN
1831-4732
https://dx.doi.org/10.2903/j.efsa.2025.9815
Herranen Anni, Rannaud-Bartaire Patricia & Fini Jean-Baptiste, juin 2025 — The thyroid hormone system and its disruption. Annales D’endocrinologie vol. 86, n° 3, p. 101773
ISSN
2213-3941
https://dx.doi.org/10.1016/j.ando.2025.101773
Krief Sabrina, Spirhanzlova Petra & Fini Jean-Baptiste, juin 2025 — Crisis on the Planet of the Apes-Plastic, the new threat?. INTRODUCTION: Chimpanzees, our closest relatives, are threatened with extinction by poaching, zoonoses, fragmentation and the… Annales D’endocrinologie vol. 86, n° 3, p. 101778
ISSN
2213-3941
https://dx.doi.org/10.1016/j.ando.2025.101778
Carrara Mathieu, Gaillard Anne-Laure, Brion Alice, Duvernois-Berthet Evelyne, Giovannangeli Carine, Concordet Jean-Paul & Pézeron Guillaume, février 2025 — Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish. Double strand breaks (DSBs) are the most deleterious DNA lesions as they frequently result in mutations when repaired by… Scientific Reports vol. 15, n° 1, p. 4886
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-025-88564-6
Dufour Sylvie, Sachs Laurent, Martin Patrick & Rousseau Karine, 2025 — [Metamorphoses in fishes and their endocrine regulations]. The most emblematic metamorphoses in the animal kingdom remain those of the caterpillar into a butterfly and the tadpole into a… Biologie Aujourd'hui vol. 219, n° 1, p. 37-50
ISSN
2105-0686
https://dx.doi.org/10.1051/jbio/2025002
Ullrich Simon, Leidescher Susanne, Feodorova Yana, Thanisch Katharina, Fini Jean-Baptiste, Kaspers Bernd, Weber Frank, Markova Boyka, Führer Dagmar, Romitti Mirian, Krebs Stefan, Blum Helmut, Leonhardt Heinrich, Costagliola Sabine, Heuer Heike et al., 2025 — Corrigendum: The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes. [This corrects the article DOI: 10.3389/fcell.2023.1265407.]. Frontiers in Cell and Developmental Biology vol. 13, , p. 1571466
ISSN
2296-634X
https://dx.doi.org/10.3389/fcell.2025.1571466
Lötters Stefan, Böning Philipp, Bailon Salvador, Castañeda Jose Daniel Barros, Boistel Renaud, Catenazzi Alessandro, Chaparro Juan C., Chávez Germán, Chujutalli Angel, Coen Laurent, Coloma Luis A., Crawford Andrew J., Culebras Jaime, Martínez Juan Carlos Cusi, Daza Juan Manuel et al., janvier 2025 — A roadmap for harlequin frog systematics, with a partial revision of Amazonian species related to Atelopus spumarius. Harlequin frogs, genus Atelopus, are a species-rich group of bufonid anurans from the Neotropics with more than 100 species… Zootaxa vol. 5571, n° 1, p. 1-76
ISSN
1175-5334
https://dx.doi.org/10.11646/zootaxa.5571.1.1
Pesce Elise, Benitez-Gonzalez Jessica, Tindall Andrew J., Lemkine Gregory F., Robin-Duchesne Barbara, Sachs Laurent M. & Pasquier Et David Du, septembre 2024 — Testing the sensitivity of the medaka Transgenic Eleuthero-embryonic THYroid-Specific assay (TETHYS) to different mechanisms of action. There are many concerns about the impacts of Endocrine-Disrupting Chemicals on both wildlife and human populations. A plethora… vol. 276, , p. 107081
ISSN
1879-1514
https://dx.doi.org/10.1016/j.aquatox.2024.107081
Louis Emeric, Fu Liezhen, Shi Yun-Bo & Sachs Laurent M, septembre 2024 — Functions and Mechanism of Thyroid Hormone Receptor Action During Amphibian Development. Abstract Thyroid hormones and their receptors (TRs) play critical roles during vertebrate development. One of the most dramatic… Endocrinology vol. 165, n° 11, bqae137
ISSN
1945-7170
https://dx.doi.org/10.1210/endocr/bqae137
Chevalier Nicolas, Guillou Pauline, Viguié Catherine, Fini Jean-Baptiste, Sachs Laurent M., Michel-Caillet Cécile & Mhaouty-Kodja Sakina, juin 2024 — Lithium and endocrine disruption: A concern for human health?. Lithium is a key medication for the treatment of psychiatric disorders and is also used in various industrial applications … Environment International , , p. 108861
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2024.108861
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  • Gladys ALFAMA
  • Anne BACHELOT
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Mathieu CARRARA
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • Stephan COUDERQ
  • Barbara DEMENEIX
  • Evelyne DUVERNOIS-BERTHET
  • Jean-Baptiste FINI
  • Anastasia FONTAINE
  • Anne-Laure GAILLARD
  • Fabrice GIRARDOT
  • Clélia GUITTONNEAU
  • Anni HERRANEN
  • Karine LE BLAY
  • Michelle LEEMANS
  • Sébastien LE MEVEL
  • Giovanni LEVI
  • Emeric LOUIS
  • Nicolas NARBOUX-NÊME
  • Louise PERICARD
  • Elise PESCE
  • Guillaume PÉZERON
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Karine ROUSSEAU
  • Laurent SACHS
  • Isabelle SEUGNET
  • Hervé TOSTIVINT
  • Alicia TRIBONDEAU
  • Pieter VANCAMP

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