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Physiologie moléculaire et adaptation
UMR 7221

Recherche

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Vancamp Pieter, Spirhanzlova Petra, Sébillot Anthony, Butruille Lucile, Gothié Jean-David, Le Mével Sébastien, Leemans Michelle, Wejaphikul Karn, Meima Marcel, Mughal Bilal B., Roques Pierre, Remaud Sylvie, Fini Jean-Baptiste & Demeneix Barbara A., 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2021.117654
Trzaska Carole, Amand Séverine, Bailly Christine, Leroy Catherine, Marchand Virginie, Duvernois-Berthet Evelyne, Saliou Jean-Michel, Benhabiles Hana, Werkmeister Elisabeth, Chassat Thierry, Guilbert Romain, Hannebique David, Mouray Anthony, Copin Marie-Christine, Moreau Pierre-Arthur et al., 2020 — 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nonsense mutations cause about 10\% of genetic disease cases, and no treatments are available. Nonsense mutations can be… Nat Commun. vol. 11, n° 1, p. 1509
ISSN
2041-1723
https://dx.doi.org/10.1038/s41467-020-15140-z
Buffet Jean-Philippe, Corre Erwan, Duvernois-Berthet Evelyne, Fournier Jérôme & Lopez Pascal Jean, 2017 — Adhesive gland transcriptomics uncovers a diversity of genes involved in glue formation in marine tube-building polychaetes. Tube-building sabellariid polychaetes are hermatypic organisms capable of forming vast reefs in highly turbulent marine… Acta Biomater. vol. 72, , p. 316-328
ISSN
1878-7568
https://dx.doi.org/10.1016/j.actbio.2018.03.037
Qiao Qin, Le Manach Séverine, Huet Hélène, Duvernois-Berthet Evelyne, Chaouch Soraya, Duval Charlotte, Sotton Benoit, Ponger Loïc, Marie Arul, Mathéron Lucrèce, Lennon Sarah, Bolbach Gérard, Djediat Chakib, Bernard Cécile, Edery Marc et al., 2016 — An integrated omic analysis of hepatic alteration in medaka fish chronically exposed to cyanotoxins with possible mechanisms of reproductive toxicity. Cyanobacterial blooms threaten human health as well as the population of other living organisms in the aquatic environment,… Environ Pollut. vol. 219, , p. 119-131
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2016.10.029
Arivalagan Jaison, Yarra Tejaswi, Marie Benjamin, Sleight Victoria A., Duvernois-Berthet Evelyne, Clark Melody S., Marie Arul & Berland Sophie, 2017 — Insights from the Shell Proteome: Biomineralization to Adaptation. Bivalves have evolved a range of complex shell forming mechanisms that are reflected by their incredible diversity in shell… Sci Rep. vol. 34, n° 1, p. 66-77
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msw219
Kortenkamp Andreas, Axelstad Marta, Baig Asma H., Bergman Åke, Bornehag Carl-Gustaf, Cenijn Peter, Christiansen Sofie, Demeneix Barbara, Derakhshan Arash, Fini Jean-Baptiste, Frädrich Caroline, Hamers Timo, Hellwig Lina, Köhrle Josef, Korevaar Tim I. M. et al., 2020 — Removing Critical Gaps in Chemical Test Methods by Developing New Assays for the Identification of Thyroid Hormone System-Disrupting Chemicals-The ATHENA Project. The test methods that currently exist for the identification of thyroid hormone system-disrupting chemicals are woefully… Int J Mol Sci vol. 21, n° 9, E3123
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms21093123
Leemans Michelle, Couderq Stephan, Demeneix Barbara & Fini Jean-Baptiste, 2019 — Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data. Plant Protection Products, more commonly referred to as pesticides and biocides, are used to control a wide range of yield… Front Endocrinol (Lausanne) vol. 10, , p. 743
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2019.00743
Spirhanzlova Petra, Fini Jean-Baptiste, Demeneix Barbara, Lardy-Fontan Sophie, Vaslin-Reimann Sophie, Lalere Béatrice, Guma Nelson, Tindall Andrew & Krief Sabrina, août 2019 — Composition and endocrine effects of water collected in the Kibale national park in Uganda. Pesticides are used worldwide with potential harmful effects on both fauna and flora. The Kibale National Park in Uganda, a… Environ. Pollut. vol. 251, , p. 460-468
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2019.05.006
Mughal Bilal B., Leemans Michelle, Spirhanzlova Petra, Demeneix Barbara & Fini Jean-Baptiste, 2018 — Reference gene identification and validation for quantitative real-time PCR studies in developing Xenopus laevis. Reference genes are essential for gene expression analysis when using real-time quantitative PCR (RT-qPCR). Xenopus laevis is… Sci Rep vol. 8, n° 1, p. 496
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-017-18684-1
Usal Marie, Veyrenc Sylvie, Darracq-Ghitalla-Ciock Marie, Regnault Christophe, Sroda Sophie, Fini Jean-Baptiste, Canlet Cécile, Tremblay-Franco Marie, Raveton Muriel & Reynaud Stéphane, 2021 — Transgenerational metabolic disorders and reproduction defects induced by benzo[a]pyrene in Xenopus tropicalis. Metabolic disorders induced by endocrine disruptors (ED) may contribute to amphibian population declines but no… Environ Pollut vol. 269, , p. 116109
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2020.116109
Mustieles Vicente, D’Cruz Shereen Cynthia, Couderq Stephan, Rodríguez-Carrillo Andrea, Fini Jean-Baptiste, Hofer Tim, Steffensen Inger-Lise, Dirven Hubert, Barouki Robert, Olea Nicolás, Fernández Mariana F. & David Arthur, 2020 — Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring. Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to bisphenol A (BPA). Moreover, BPA… Environ Int vol. 144, , p. 105811
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2020.105811
Qiao Qin, Le Manach Séverine, Sotton Benoit, Huet Hélène, Duvernois-Berthet Evelyne, Paris Alain, Duval Charlotte, Ponger Loïc, Marie Arul, Blond Alain, Mathéron Lucrèce, Vinh Joelle, Bolbach Gérard, Djediat Chakib, Bernard Cécile et al., 2016 — Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach. Sexual dimorphism describes the features that discriminate between the two sexes at various biological levels. Especially,… Sci Rep. vol. 6, , p. 32459
ISSN
2045-2322
https://dx.doi.org/10.1038/srep32459
Bussard Adrien, Corre Erwan, Hubas Cédric, Duvernois-Berthet Evelyne, Le Corguillé Gildas, Jourdren Laurent, Coulpier Fanny, Claquin Pascal & Lopez Pascal Jean, 2017 — Physiological adjustments and transcriptome reprogramming are involved in the acclimation to salinity gradients in diatoms. Salinity regimes in estuaries and coastal areas vary with river discharge patterns, seawater evaporation, the morphology of… Environ Microbiol. vol. 19, n° 3, p. 909-925
ISSN
1462-2920
https://dx.doi.org/10.1111/1462-2920.13398
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, octobre 2022 — Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
ISSN
1664-8021
https://dx.doi.org/10.3389/fgene.2022.996826
Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., novembre 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, juin 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
ISSN
1097-0177
https://dx.doi.org/10.1002/dvdy.304
Delfosse Vanessa, Huet Tiphaine, Harrus Deborah, Granell Meritxell, Bourguet Maxime, Gardia-Parège Caroline, Chiavarina Barbara, Grimaldi Marina, Le Mével Sébastien, Blanc Pauline, Huang David, Gruszczyk Jakub, Demeneix Barbara, Cianférani Sarah, Fini Jean-Baptiste et al., 2021 — Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Humans are chronically exposed to mixtures of xenobiotics referred to as endocrine-disrupting chemicals (EDCs). A vast body of… Proc Natl Acad Sci USA vol. 118, n° 1, e2020551118
ISSN
1091-6490
https://dx.doi.org/10.1073/pnas.2020551118
Krief Sabrina, Iglesias-González Alba, Appenzeller Brice MarcRené, Okimat John Paul, Fini Jean-Baptiste, Demeneix Barbara, Vaslin-Reimann Sophie, Lardy-Fontan Sophie, Guma Nelson & Spirhanzlova Petra, mai 2020 — Road impact in a protected area with rich biodiversity: the case of the Sebitoli road in Kibale National Park, Uganda. While road network expansion is crucial for economic development, it can cause a notable disturbance of fauna, especially in… Environ Sci Pollut Res Int vol. 27, n° 22, p. 27914-27925
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-020-09098-0
Babajko Sylvie, Gayrard Véronique, Houari Sophia, Thu Bui Ai, Barouki Robert, Niederreither Karen, Fini Jean-Baptiste, Dursun Elisabeth & Coumoul Xavier, mars 2020 — [Oral cavity as a target and a marker of environmental exposures: developmental dental defects]. The oral cavity is one of the main route for environmental contaminations associated to many chronic diseases (cancers,… Med Sci (Paris) vol. 36, n° 3, p. 225-230
ISSN
1958-5381
https://dx.doi.org/10.1051/medsci/2020024
Couderq Stephan, Leemans Michelle & Fini Jean-Baptiste, mai 2020 — Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models. Thyroid hormones (THs) play critical roles in profound changes in many vertebrates, notably in mammalian neurodevelopment,… Mol. Cell. Endocrinol. vol. 508, , p. 110779
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2020.110779
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Par auteurs

  • Gladys ALFAMA
  • Anne BACHELOT
  • Nicolas BUISINE
  • Lucile BUTRUILLE
  • Mathieu CARRARA
  • Lamis CHAMAS
  • Marie-Stéphanie CLERGET-FROIDEVAUX
  • Laurent COEN
  • Stephan COUDERQ
  • Barbara DEMENEIX
  • Evelyne DUVERNOIS-BERTHET
  • Jean-Baptiste FINI
  • Anastasia FONTAINE
  • Anne-Laure GAILLARD
  • Fabrice GIRARDOT
  • Anni HERRANEN
  • Karine LE BLAY
  • Michelle LEEMANS
  • Sébastien LE MEVEL
  • Giovanni LEVI
  • Nicolas NARBOUX-NÊME
  • Louise PERICARD
  • Elise PESCE
  • Guillaume PÉZERON
  • Sylvie REMAUD
  • Muriel RIGOLET
  • Laurent SACHS
  • Isabelle SEUGNET
  • Hervé TOSTIVINT
  • Alicia TRIBONDEAU
  • Pieter VANCAMP

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