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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., November 2022 — Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms232213715
Marasco Valeria, Sebastiano Manrico, Costantini David, Pola Gianni & Fusani Leonida, 2021 — Controlled expression of the migratory phenotype affects oxidative status in birds. High caloric intake can increase production of reactive oxygen and nitrogen species. We examined whether the emergence of the… J Exp Biol vol. 224, , jeb233486
ISSN
1477-9145
https://dx.doi.org/10.1242/jeb.233486
Fritze Marcus, Puechmaille Sebastien J., Costantini David, Fickel Jörns, Voigt Christian C. & Czirják Gábor Á, 2021 — Determinants of defence strategies of a hibernating European bat species towards the fungal pathogen Pseudogymnoascus destructans. Pseudogymnoascus destructans (Pd), the causative agent of white-nose syndrome in North America, has decimated bat populations… Dev Comp Immunol vol. 119, , p. 104017
ISSN
1879-0089
https://dx.doi.org/10.1016/j.dci.2021.104017
Sebastiano Manrico, Canestrelli Daniele, Bisconti Roberta, Lavergne Anne, Pineau Kévin, Chastel Olivier, Lacoste Vincent & Costantini David, 2020 — Detection and Phylogenetic Characterization of a Novel Herpesvirus in Sooty Terns Onychoprion fuscatus. Since 2005, we have recorded annual episodes of alphaherpesvirus outbreaks in chicks of magnificent frigatebird Fregata… Front Vet Sci. vol. 7, , p. 567
ISSN
2297-1769
https://dx.doi.org/10.3389/fvets.2020.00567
Liparoto Anita, Canestrelli Daniele, Bisconti Roberta, Carere Claudio & Costantini David, 2020 — Biogeographic history moulds population differentiation in ageing of oxidative status in an amphibian. Regulation of oxidative status plays a substantial role in physiological ageing. However, we know little about age-related… J Exp Biol vol. 223, , jeb235002
ISSN
1477-9145
https://dx.doi.org/10.1242/jeb.235002
Soldatini Cecilia, Sebastiano Manrico, Albores-Barajas Yuri V., Abdelgawad Hamada, Bustamante Paco & Costantini David, March 2020 — Mercury exposure in relation to foraging ecology and its impact on the oxidative status of an endangered seabird. Mercury is a natural element extensively found in the Earth’s crust, released to the atmosphere and waters by natural processes… Sci. Total Environ. vol. 724, , p. 138131
ISSN
1879-1026
https://dx.doi.org/10.1016/j.scitotenv.2020.138131
Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, June 2021 — Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
ISSN
1097-0177
https://dx.doi.org/10.1002/dvdy.304
Demeneix Barbara, Vandenberg Laura N., Ivell Richard & Zoeller R. Thomas, October 2020 — Thresholds and Endocrine Disruptors: An Endocrine Society Policy Perspective. The concept of a threshold of adversity in toxicology is neither provable nor disprovable. As such, it is not a scientific… J Endocr Soc . vol. 4, n° 10, bvaa085
ISSN
2472-1972
https://dx.doi.org/10.1210/jendso/bvaa085
Landrigan Philip J., Stegeman John J., Fleming Lora E., Allemand Denis, Anderson Donald M., Backer Lorraine C., Brucker-Davis Françoise, Chevalier Nicolas, Corra Lilian, Czerucka Dorota, Bottein Marie-Yasmine Dechraoui, Demeneix Barbara, Depledge Michael, Deheyn Dimitri D., Dorman CharlesJ. et al., 2020 — Human Health and Ocean Pollution. Background: Pollution - unwanted waste released to air, water, and land by human activity - is the largest environmental cause… Ann Glob Health vol. 86, n° 1, p. 151
ISSN
2214-9996
https://dx.doi.org/10.5334/aogh.2831
Delfosse Vanessa, Huet Tiphaine, Harrus Deborah, Granell Meritxell, Bourguet Maxime, Gardia-Parège Caroline, Chiavarina Barbara, Grimaldi Marina, Le Mével Sébastien, Blanc Pauline, Huang David, Gruszczyk Jakub, Demeneix Barbara, Cianférani Sarah, Fini Jean-Baptiste et al., 2021 — Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Humans are chronically exposed to mixtures of xenobiotics referred to as endocrine-disrupting chemicals (EDCs). A vast body of… Proc Natl Acad Sci USA vol. 118, n° 1, e2020551118
ISSN
1091-6490
https://dx.doi.org/10.1073/pnas.2020551118
Lupu Diana, Andersson Patrik, Bornehag Carl-Gustaf, Demeneix Barbara, Fritsche Ellen, Gennings Chris, Lichtensteiger Walter, Leist Marcel, Leonards Pim E. G., Ponsonby Anne-Louise, Scholze Martin, Testa Giuseppe, Tresguerres Jesus A. F., Westerink Remco H. S., Zalc Bernard et al., June 2020 — The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity. Ubiquitous exposure to endocrine-disrupting chemicals (EDCs) has caused serious concerns about the ability of these chemicals… Int J Mol Sci vol. 21, n° 11, p. 3978
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms21113978
Krief Sabrina, Iglesias-González Alba, Appenzeller Brice MarcRené, Okimat John Paul, Fini Jean-Baptiste, Demeneix Barbara, Vaslin-Reimann Sophie, Lardy-Fontan Sophie, Guma Nelson & Spirhanzlova Petra, May 2020 — Road impact in a protected area with rich biodiversity: the case of the Sebitoli road in Kibale National Park, Uganda. While road network expansion is crucial for economic development, it can cause a notable disturbance of fauna, especially in… Environ Sci Pollut Res Int vol. 27, n° 22, p. 27914-27925
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-020-09098-0
Babajko Sylvie, Gayrard Véronique, Houari Sophia, Thu Bui Ai, Barouki Robert, Niederreither Karen, Fini Jean-Baptiste, Dursun Elisabeth & Coumoul Xavier, March 2020 — [Oral cavity as a target and a marker of environmental exposures: developmental dental defects]. The oral cavity is one of the main route for environmental contaminations associated to many chronic diseases (cancers,… Med Sci (Paris) vol. 36, n° 3, p. 225-230
ISSN
1958-5381
https://dx.doi.org/10.1051/medsci/2020024
Couderq Stephan, Leemans Michelle & Fini Jean-Baptiste, May 2020 — Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models. Thyroid hormones (THs) play critical roles in profound changes in many vertebrates, notably in mammalian neurodevelopment,… Mol. Cell. Endocrinol. vol. 508, , p. 110779
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2020.110779
Levi Giovanni, de Lombares Camille, Giuliani Cristina, Iannuzzi Vincenzo, Aouci Rym, Garagnani Paolo, Franceschi Claudio, Grimaud-Hervé Dominique & Narboux-Nême Nicolas, 2021 — DLX 5/6 GABAergic expression affects social vocalization: implications for human evolution. DLX 5 and DLX6 are two closely related transcription factors involved in brain development and in GABAergic differentiation… Mol. Biol. Evol. , , msab181
ISSN
1537-1719
https://dx.doi.org/10.1093/molbev/msab181
Costantini David, Masi Shelly, Rachid Lyna, Beltrame Marielle, Rohmer Mélanie & Krief Sabrina, 2021 — Mind the food: rapid changes in antioxidant content of diet affect oxidative status of chimpanzees. The link between dietary antioxidants and oxidative status has been studied extensively in humans. Surprisingly, comparative… Am J Physiol Regul Integr Comp Physiol vol. 320, n° 5, R728–R734
ISSN
1522-1490
https://dx.doi.org/10.1152/ajpregu.00003.2021
Sobrido-Cameán D., Yáñez-Guerra L. A., Deber A., Freire-Delgado M., Cacheiro-Vázquez R., Rodicio M. C., Tostivint H., Anadón R. & Barreiro-Iglesias A., February 2021 — Differential expression of somatostatin genes in the central nervous system of the sea lamprey. The identification of three somatostatin (SST) genes (SSTa, SSTb, and SSTc) in lampreys (Tostivint et al. Gen Comp Endocrinol… Brain Struct Funct , ,
ISSN
1863-2661
https://dx.doi.org/10.1007/s00429-021-02224-9
Quan Feng B., Desban Laura, Mirat Olivier, Kermarquer Maxime, Roussel Julian, Koëth Fanny, Marnas Hugo, Djenoune Lydia, Lejeune François-Xavier, Tostivint Hervé & Wyart Claire, September 2020 — Somatostatin 1.1 contributes to the innate exploration of zebrafish larva. Pharmacological experiments indicate that neuropeptides can effectively tune neuronal activity and modulate locomotor output… Sci Rep vol. 10, n° 1, p. 15235
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-020-72039-x
Sebastiano Manrico, Costantini David, Eens Marcel, Pineau Kevin, Bustamante Paco & Chastel Olivier, June 2022 — Possible interaction between exposure to environmental contaminants and nutritional stress in promoting disease occurrence in seabirds from French Guiana: a review. Reg Environ Change vol. 22, n° 2, p. 63
ISSN
1436-3798, 1436-378X
https://dx.doi.org/10.1007/s10113-022-01914-2
Andersen Helle Raun, David Arthur, Freire Carmen, Fernández Mariana F., D’Cruz Shereen Cynthia, Reina-Pérez Iris, Fini Jean-Baptiste & Blaha Ludek, November 2022 — Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence. BACKGROUND : Pyrethroid metabolites are widely detectable in urine from the general population, including pregnant women and… Environmental Research vol. 214, , p. 113935
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2022.113935
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