Vancamp Pieter, Spirhanzlova Petra, Sébillot Anthony, Butruille Lucile, Gothié Jean-David, Le Mével Sébastien, Leemans Michelle, Wejaphikul Karn, Meima Marcel, Mughal Bilal B., Roques Pierre, Remaud Sylvie, Fini Jean-Baptiste & Demeneix Barbara A., 2021 — The pyriproxyfen metabolite, 4’-OH-PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection. North-Eastern Brazil saw intensive application of the insecticide pyriproxyfen (PPF) during the microcephaly outbreak caused… Environ Pollut. vol. 285, , p. 117654
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2021.117654
Derakhshan Arash, Shu Huan, Broeren Maarten A. C., Lindh Christian H., Peeters Robin P., Kortenkamp Andreas, Demeneix Barbara, Bornehag Carl-Gustaf & Korevaar Tim I. M., December 2021 — Association of phthalate exposure with thyroid function during pregnancy. BACKGROUND : The extent of thyroid disruptive effects of phthalates during pregnancy remains unclear. AIM: To investigate the… Environ Int. vol. 157, , p. 106795
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2021.106795
Delfosse Vanessa, Huet Tiphaine, Harrus Deborah, Granell Meritxell, Bourguet Maxime, Gardia-Parège Caroline, Chiavarina Barbara, Grimaldi Marina, Le Mével Sébastien, Blanc Pauline, Huang David, Gruszczyk Jakub, Demeneix Barbara, Cianférani Sarah, Fini Jean-Baptiste et al., 2021 — Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Humans are chronically exposed to mixtures of xenobiotics referred to as endocrine-disrupting chemicals (EDCs). A vast body of… Proc Natl Acad Sci USA vol. 118, n° 1, e2020551118
ISSN
1091-6490
https://dx.doi.org/10.1073/pnas.2020551118
Luongo Cristina, Butruille Lucile, Sébillot Anthony, LeBlay Karine, Schwaninger Markus, Heuer Heike, Demeneix Barbara A. & Remaud Sylvie, February 2021 — Absence of Both Thyroid Hormone Transporters MCT8 and OATP1C1 Impairs Neural Stem Cell Fate in the Adult Mouse Subventricular Zone. Adult neural stem cell (NSC) generation in vertebrate brains requires thyroid hormones (THs). How THs enter the NSC population… Stem Cell Reports vol. 16, n° 2, p. 337-353
ISSN
2213-6711
https://dx.doi.org/10.1016/j.stemcr.2020.12.009
Butruille Lucile, Vancamp Pieter, Demeneix Barbara A. & Remaud Sylvie, 2021 — Thyroid hormone regulation of adult neural stem cell fate: A comparative analysis between rodents and primates. Thyroid hormone (TH) signaling, a highly conserved pathway across vertebrates, is crucial for brain development and function… Vitam Horm . vol. 116, , p. 133-192
ISSN
0083-6729
https://dx.doi.org/10.1016/bs.vh.2021.02.009