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PhyMA is a laboratory under the dual supervision of the CNRS (INEE) and the National Museum of Natural History.
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Physiologie moléculaire et adaptation
UMR 7221

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Lo Iacono Nadia, Mantero Stefano, Chiarelli Anna, Garcia Elvin, Mills Alea A., Morasso Maria I., Costanzo Antonio, Levi Giovanni, Guerrini Luisa & Merlo Giorgio R., April 2008 — Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development vol. 135, n° 7, p. 1377-1388
ISSN
0950-1991
https://dx.doi.org/10.1242/dev.011759
Suzuki Kentaro, Haraguchi Ryuma, Ogata Tsutomu, Barbieri Ottavia, Alegria Olinda, Vieux-Rochas Maxence, Nakagata Naomi, Ito Masataka, Mills Alea A., Kurita Takeshi, Levi Giovanni & Yamada Gen, January 2008 — Abnormal urethra formation in mouse models of split-hand/split-foot malformation type 1 and type 4. Eur. J. Hum. Genet. vol. 16, n° 1, p. 36-44
ISSN
1018-4813
https://dx.doi.org/10.1038/sj.ejhg.5201925
Havis Emmanuelle, Bilesimo Patrice, Demeneix Barbara A. & Sachs Laurent M., 2008 — [Mechanisms underlying thyroid hormone response gene regulation during amphibian development]. J. Soc. Biol. vol. 202, n° 2, p. 73-81
ISSN
1295-0661
https://dx.doi.org/10.1051/jbio:2008009
Bagamasbad Pia, Howdeshell Kembra L., Sachs Laurent M., Demeneix Barbara A. & Denver Robert J., January 2008 — A role for basic transcription element-binding protein 1 (BTEB1) in the autoinduction of thyroid hormone receptor beta. J. Biol. Chem. vol. 283, n° 4, p. 2275-2285
ISSN
0021-9258
https://dx.doi.org/10.1074/jbc.M709306200
Bertrand Stéphanie, Thisse Bernard, Tavares Raquel, Sachs Laurent, Chaumot Arnaud, Bardet Pierre-Luc, Escrivà Héctor, Duffraisse Maryline, Marchand Oriane, Safi Rachid, Thisse Christine & Laudet Vincent, November 2007 — Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression. PLoS Genet. vol. 3, n° 11, e188
ISSN
1553-7404
https://dx.doi.org/10.1371/journal.pgen.0030188
Vieux-Rochas Maxence, Coen Laurent, Sato Takahiro, Kurihara Yukiko, Gitton Yorick, Barbieri Ottavia, Le Blay Karine, Merlo Giorgio, Ekker Marc, Kurihara Hiroki, Janvier Philippe & Levi Giovanni, June 2007 — Molecular dynamics of retinoic acid-induced craniofacial malformations: implications for the origin of gnathostome jaws. PLoS ONE vol. 2, n° 6, e510
ISSN
1932-6203
https://dx.doi.org/10.1371/journal.pone.0000510
Coen Laurent, Le Blay Karine, Rowe Isaline & Demeneix Barbara A., May 2007 — Caspase-9 regulates apoptosis/proliferation balance during metamorphic brain remodeling in Xenopus. Proc. Natl. Acad. Sci. U.S.A. vol. 104, n° 20, p. 8502-8507
ISSN
0027-8424
https://dx.doi.org/10.1073/pnas.0608877104
Du Pasquier D., Chesneau A., Ymlahi-Ouazzani Q., Boistel R., Pollet N., Ballagny C., Sachs L. M., Demeneix B. & Mazabraud A., January 2007 — tBid mediated activation of the mitochondrial death pathway leads to genetic ablation of the lens in Xenopus laevis. Genesis vol. 45, n° 1, p. 1-10
ISSN
1526-954X
https://dx.doi.org/10.1002/dvg.20252
Samee Nadeem, de Vernejoul Marie-Christine & Levi Giovanni, 2007 — Role of DLX regulatory proteins in osteogenesis and chondrogenesis. Crit. Rev. Eukaryot. Gene Expr. vol. 17, n° 3, p. 173-186
ISSN
1045-4403
Hsu Shu-Hsuan Claire, Noamani Babak, Abernethy Danielle E., Zhu Hui, Levi Giovanni & Bendall Andrew J., November 2006 — Dlx5- and Dlx6-mediated chondrogenesis: Differential domain requirements for a conserved function. Mech. Dev. vol. 123, n° 11, p. 819-830
ISSN
0925-4773
https://dx.doi.org/10.1016/j.mod.2006.08.005
Havis Emmanuelle, Le Mevel Sébastien, Morvan Dubois Ghislaine, Shi De-Li, Scanlan Thomas S., Demeneix Barbara A. & Sachs Laurent M., October 2006 — Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development. EMBO J. vol. 25, n° 20, p. 4943-4951
ISSN
0261-4189
https://dx.doi.org/10.1038/sj.emboj.7601356
Froidevaux Marie-Stéphanie Clerget, Berg Petra, Seugnet Isabelle, Decherf Stéphanie, Becker Nathalie, Sachs LaurentM., Bilesimo Patrice, Nygård Maria, Pongratz Ingemar & Demeneix Barbara A., October 2006 — The co-chaperone XAP2 is required for activation of hypothalamic thyrotropin-releasing hormone transcription in vivo. EMBO Rep. vol. 7, n° 10, p. 1035-1039
ISSN
1469-221X
https://dx.doi.org/10.1038/sj.embor.7400778
Du Pasquier D., Rincheval V., Sinzelle L., Chesneau A., Ballagny C., Sachs L. M., Demeneix B. & Mazabraud A., August 2006 — Developmental cell death during Xenopus metamorphosis involves BID cleavage and caspase 2 and 8 activation. Dev. Dyn. vol. 235, n° 8, p. 2083-2094
ISSN
1058-8388
https://dx.doi.org/10.1002/dvdy.20874
Safi Rachid, Vlaeminck-Guillem Virginie, Duffraisse Marilyne, Seugnet Isabelle, Plateroti Michelina, Margotat Alain, Duterque-Coquillaud Martine, Crespi Erica J., Denver Robert J., Demeneix Barbara & Laudet Vincent, June 2006 — Pedomorphosis revisited: thyroid hormone receptors are functional in Necturus maculosus. Evol. Dev. vol. 8, n° 3, p. 284-292
ISSN
1520-541X
https://dx.doi.org/10.1111/j.1525-142X.2006.00099.x
Dif Fariel, Djediat Chakib, Alegria Olinda, Demeneix Barbara & Levi Giovanni, January 2006 — Transfection of multiple pulmonary cell types following intravenous injection of PEI-DNA in normal and CFTR mutant mice. J Gene Med vol. 8, n° 1, p. 82-89
ISSN
1099-498X
https://dx.doi.org/10.1002/jgm.831
Levi Giovanni, Mantero Stefano, Barbieri Ottavia, Cantatore Daniela, Paleari Laura, Beverdam Annemiek, Genova Francesca, Robert Benoit & Merlo Giorgio R., January 2006 — Msx1 and Dlx5 act independently in development of craniofacial skeleton, but converge on the regulation of Bmp signaling in palate formation. Mech. Dev. vol. 123, n° 1, p. 3-16
ISSN
0925-4773
https://dx.doi.org/10.1016/j.mod.2005.10.007
Lemkine G. F., Raj A., Alfama G., Turque N., Hassani Z., Alegria-Prévot O., Samarut J., Levi G. & Demeneix B. A., May 2005 — Adult neural stem cell cycling in vivo requires thyroid hormone and its alpha receptor. FASEB J. vol. 19, n° 7, p. 863-865
ISSN
1530-6860
https://dx.doi.org/10.1096/fj.04-2916fje
Rowe Isaline, Le Blay Karine, Du Pasquier David, Palmier Karima, Levi Giovanni, Demeneix Barbara & Coen Laurent, May 2005 — Apoptosis of tail muscle during amphibian metamorphosis involves a caspase 9-dependent mechanism. Dev. Dyn. vol. 233, n° 1, p. 76-87
ISSN
1058-8388
https://dx.doi.org/10.1002/dvdy.20312
Sachs Laurent M., Le Mevel Sébastien & Demeneix Barbara A., December 2004 — Implication of bax in Xenopus laevis tail regression at metamorphosis. Dev. Dyn. vol. 231, n° 4, p. 671-682
ISSN
1058-8388
https://dx.doi.org/10.1002/dvdy.20166
Dif Fariel, Marty Caroline, Baudoin Claude, de Vernejoul Marie-Christine & Levi Giovanni, September 2004 — Severe osteopenia in CFTR-null mice. Bone vol. 35, n° 3, p. 595-603
ISSN
8756-3282
https://dx.doi.org/10.1016/j.bone.2004.05.021
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