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Physiologie moléculaire et adaptation
UMR 7221

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Leemans Michelle, Couderq Stephan, Demeneix Barbara & Fini Jean-Baptiste, 2019 — Pesticides With Potential Thyroid Hormone-Disrupting Effects: A Review of Recent Data. Plant Protection Products, more commonly referred to as pesticides and biocides, are used to control a wide range of yield… Front Endocrinol (Lausanne) vol. 10, , p. 743
ISSN
1664-2392
https://dx.doi.org/10.3389/fendo.2019.00743
Spirhanzlova Petra, Fini Jean-Baptiste, Demeneix Barbara, Lardy-Fontan Sophie, Vaslin-Reimann Sophie, Lalere Béatrice, Guma Nelson, Tindall Andrew & Krief Sabrina, August 2019 — Composition and endocrine effects of water collected in the Kibale national park in Uganda. Pesticides are used worldwide with potential harmful effects on both fauna and flora. The Kibale National Park in Uganda, a… Environ. Pollut. vol. 251, , p. 460-468
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2019.05.006
Mughal Bilal B., Leemans Michelle, Spirhanzlova Petra, Demeneix Barbara & Fini Jean-Baptiste, 2018 — Reference gene identification and validation for quantitative real-time PCR studies in developing Xenopus laevis. Reference genes are essential for gene expression analysis when using real-time quantitative PCR (RT-qPCR). Xenopus laevis is… Sci Rep vol. 8, n° 1, p. 496
ISSN
2045-2322
https://dx.doi.org/10.1038/s41598-017-18684-1
Usal Marie, Veyrenc Sylvie, Darracq-Ghitalla-Ciock Marie, Regnault Christophe, Sroda Sophie, Fini Jean-Baptiste, Canlet Cécile, Tremblay-Franco Marie, Raveton Muriel & Reynaud Stéphane, 2021 — Transgenerational metabolic disorders and reproduction defects induced by benzo[a]pyrene in Xenopus tropicalis. Metabolic disorders induced by endocrine disruptors (ED) may contribute to amphibian population declines but no… Environ Pollut vol. 269, , p. 116109
ISSN
1873-6424
https://dx.doi.org/10.1016/j.envpol.2020.116109
Mustieles Vicente, D’Cruz Shereen Cynthia, Couderq Stephan, Rodríguez-Carrillo Andrea, Fini Jean-Baptiste, Hofer Tim, Steffensen Inger-Lise, Dirven Hubert, Barouki Robert, Olea Nicolás, Fernández Mariana F. & David Arthur, 2020 — Bisphenol A and its analogues: A comprehensive review to identify and prioritize effect biomarkers for human biomonitoring. Human biomonitoring (HBM) studies have demonstrated widespread and daily exposure to bisphenol A (BPA). Moreover, BPA… Environ Int vol. 144, , p. 105811
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2020.105811
Delfosse Vanessa, Huet Tiphaine, Harrus Deborah, Granell Meritxell, Bourguet Maxime, Gardia-Parège Caroline, Chiavarina Barbara, Grimaldi Marina, Le Mével Sébastien, Blanc Pauline, Huang David, Gruszczyk Jakub, Demeneix Barbara, Cianférani Sarah, Fini Jean-Baptiste et al., 2021 — Mechanistic insights into the synergistic activation of the RXR-PXR heterodimer by endocrine disruptor mixtures. Humans are chronically exposed to mixtures of xenobiotics referred to as endocrine-disrupting chemicals (EDCs). A vast body of… Proc Natl Acad Sci USA vol. 118, n° 1, e2020551118
ISSN
1091-6490
https://dx.doi.org/10.1073/pnas.2020551118
Krief Sabrina, Iglesias-González Alba, Appenzeller Brice MarcRené, Okimat John Paul, Fini Jean-Baptiste, Demeneix Barbara, Vaslin-Reimann Sophie, Lardy-Fontan Sophie, Guma Nelson & Spirhanzlova Petra, May 2020 — Road impact in a protected area with rich biodiversity: the case of the Sebitoli road in Kibale National Park, Uganda. While road network expansion is crucial for economic development, it can cause a notable disturbance of fauna, especially in… Environ Sci Pollut Res Int vol. 27, n° 22, p. 27914-27925
ISSN
1614-7499
https://dx.doi.org/10.1007/s11356-020-09098-0
Babajko Sylvie, Gayrard Véronique, Houari Sophia, Thu Bui Ai, Barouki Robert, Niederreither Karen, Fini Jean-Baptiste, Dursun Elisabeth & Coumoul Xavier, March 2020 — [Oral cavity as a target and a marker of environmental exposures: developmental dental defects]. The oral cavity is one of the main route for environmental contaminations associated to many chronic diseases (cancers,… Med Sci (Paris) vol. 36, n° 3, p. 225-230
ISSN
1958-5381
https://dx.doi.org/10.1051/medsci/2020024
Couderq Stephan, Leemans Michelle & Fini Jean-Baptiste, May 2020 — Testing for thyroid hormone disruptors, a review of non-mammalian in vivo models. Thyroid hormones (THs) play critical roles in profound changes in many vertebrates, notably in mammalian neurodevelopment,… Mol. Cell. Endocrinol. vol. 508, , p. 110779
ISSN
1872-8057
https://dx.doi.org/10.1016/j.mce.2020.110779
Andersen Helle Raun, David Arthur, Freire Carmen, Fernández Mariana F., D’Cruz Shereen Cynthia, Reina-Pérez Iris, Fini Jean-Baptiste & Blaha Ludek, November 2022 — Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence. BACKGROUND : Pyrethroid metabolites are widely detectable in urine from the general population, including pregnant women and… Environmental Research vol. 214, , p. 113935
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2022.113935
Alejevski Faredin, Leemans Michelle, Gaillard Anne-Laure, Leistenschneider David, de Flori Céline, Bougerol Marion, LeMével Sébastien, Herrel Anthony, Fini Jean-Baptiste, Pézeron Guillaume & Tostivint Hervé, August 2021 — Conserved role of the urotensin II receptor 4 signalling pathway to control body straightness in a tetrapod. Urp1 and Urp2 are two neuropeptides of the urotensin II family identified in teleost fish and mainly expressed in… Open Biology vol. 11, n° 8, p. 210065
ISSN
2046-2441
https://dx.doi.org/10.1098/rsob.210065
Tostivint Hervé, Alejevski Faredin, Leemans Michelle, Gaillard Anne-Laure, Le Mével Sébastien, Herrel Anthony, Fini Jean-Baptiste & Pézeron Guillaume, January 2022 — [Neuropeptides involved in proper spine morphogenesis: Lessons from fish and toad]. Médecine Sciences vol. 38, n° 1, p. 27-29
ISSN
1958-5381
https://dx.doi.org/10.1051/medsci/2021236
Deprouw Camille, Courties Alice, Fini Jean-Baptiste, Clerget-Froidevaux Marie-Stéphanie, Demeneix Barbara, Berenbaum Francis, Sellam Jérémie & Louati Karine, June 2022 — Pollutants: a candidate as a new risk factor for osteoarthritis-results from a systematic literature review. BACKGROUND : Considering non-classical environmental risk factors for osteoarthritis (OA), a systematic literature review … RMD Open vol. 8, n° 2, e001983
ISSN
2056-5933
https://dx.doi.org/10.1136/rmdopen-2021-001983
Leemans Michelle, Spirhanzlova Petra, Couderq Stephan, LeMével Sébastien, Grimaldi Alexis, Duvernois-Berthet Evelyne, Demeneix Barbara & Fini Jean-Baptiste, January 2023 — A Mixture of Chemicals Found in Human Amniotic Fluid Disrupts Brain Gene Expression and Behavior in Xenopus laevis. Thyroid hormones (TH) are essential for normal brain development, influencing neural cell differentiation, migration, and… Int J Mol Sci. vol. 24, n° 3, p. 2588
ISSN
1422-0067
https://dx.doi.org/10.3390/ijms24032588
Vancamp Pieter, Butruille Lucile, Herranen Anni, Boelen Anita, Fini Jean-Baptiste, Demeneix Barbara A. & Remaud Sylvie, January 2023 — Transient developmental exposure to low doses of bisphenol F negatively affects neurogliogenesis and olfactory behaviour in adult mice. Neural stem cells in the murine subventricular zone (SVZ) reactivate during postnatal development to generate neurons and glia… Environ Int . vol. 172, , p. 107770
ISSN
1873-6750
https://dx.doi.org/10.1016/j.envint.2023.107770
Rodríguez-Carrillo Andrea, Mustieles Vicente, Salamanca-Fernández Elena, Olivas-Martínez Alicia, Suárez Beatriz, Bajard Lola, Baken Kirsten, Blaha Ludek, Bonefeld-Jørgensen Eva Cecilie, Couderq Stephan, D’Cruz ShereenCynthia, Fini Jean-Baptiste, Govarts Eva, Gundacker Claudia, Hernández Antonio F. et al., February 2023 — Implementation of effect biomarkers in human biomonitoring studies: A systematic approach synergizing toxicological and epidemiological knowledge. Human biomonitoring (HBM) studies have highlighted widespread daily exposure to environmental chemicals. Some of these are… Int J Hyg Environ Health vol. 249, , p. 114140
ISSN
1618-131X
https://dx.doi.org/10.1016/j.ijheh.2023.114140
Pasquier Elodie, Viguié Catherine, Fini Jean-Baptiste, Mhaouty-Kodja Sakina & Michel-Caillet Cécile, March 2023 — Limits of the regulatory evaluation of resorcinol as a thyroid disruptor: When limited experimental data challenge established effects in humans. Severe hypothyroidism has been reported in humans during resorcinol therapeutic use. However, available data highlight… Environ Res vol. 222, , p. 115330
ISSN
1096-0953
https://dx.doi.org/10.1016/j.envres.2023.115330
Sapounidou Maria, Andersson Patrik L., Leemans Michelle, Fini Jean-Baptiste, Demeneix Barbara, Rüegg Joëlle, Bornehag Carl-Gustaf & Gennings Chris, March 2023 — From Cohort to Cohort: A Similar Mixture Approach (SMACH) to Evaluate Exposures to a Mixture Leading to Thyroid-Mediated Neurodevelopmental Effects Using NHANES Data. Prenatal exposure to a mixture (MIX N) of eight endocrine-disrupting chemicals has been associated with language delay in… Toxics vol. 11, n° 4, p. 331
ISSN
2305-6304
https://dx.doi.org/10.3390/toxics11040331
Ullrich Simon, Leidescher Susanne, Feodorova Yana, Thanisch Katharina, Fini Jean-Baptiste, Kaspers Bernd, Weber Frank, Markova Boyka, Führer Dagmar, Romitti Mirian, Krebs Stefan, Blum Helmut, Leonhardt Heinrich, Costagliola Sabine, Heuer Heike et al., 2023 — The highly and perpetually upregulated thyroglobulin gene is a hallmark of functional thyrocytes. Abnormalities are indispensable for studying normal biological processes and mechanisms. In the present work, we draw attention… vol. 11, , p. 1265407
ISSN
2296-634X
https://dx.doi.org/10.3389/fcell.2023.1265407
Rannaud-Bartaire Patricia & Fini Jean-Baptiste, 2023 — [Disruptors of thyroid hormones: Which consequences for human health and environment?]. Endocrine disruptors (EDs) of chemical origin are the subject of numerous studies, some of which have led to measures aimed at… Bio Aujourd'hui vol. 217, n° 3, p. 219-231
ISSN
2105-0686
https://dx.doi.org/10.1051/jbio/2023036
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