Affiliation entity
Accreditation to supervise research
Physiologie comparée, Analyses génomiques structurales et fonctionnelles, Boinformatique



7 rue Cuvier

75005 Paris

Responsibilities inside unit

Correspondant informatique

Responsibilities outside unit

Responsable Cluster Calcul scientifique



  • Bredeson Jessen V., Mudd Austin B., Medina-Ruiz Sofia, Mitros Therese, Smith Owen Kabnick, Miller Kelly E., Lyons Jessica B., Batra Sanjit S., Park Joseph, Berkoff Kodiak C., Plott Christopher, Grimwood Jane, Schmutz Jeremy, Aguirre-Figueroa Guadalupe, Khokha Mustafa K. et al., January 2024Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs. Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate… Nat. Commun. vol. 15, n° 1, p. 579
  • Lazcano I., Olvera A., Pech-Pool S. M., Sachs L., Buisine N. & Orozco A., 2023Differential effects of 3,5-T2 and T3 on the gill regeneration and metamorphosis of the Ambystoma mexicanum (axolotl). Thyroid hormones (THs) regulate tissue remodeling processes during early- and post-embryonic stages in vertebrates. The Mexican… Front Endocrinol (Lausanne) vol. 14, , p. 1208182
  • Rigolet Muriel, Buisine Nicolas, Scharwatt Marylou, Duvernois-Berthet Evelyne, Buchholz Daniel R. & Sachs Laurent M., November 2022Crosstalk between Thyroid Hormone and Corticosteroid Signaling Targets Cell Proliferation in Xenopus tropicalis Tadpole Liver. Thyroid hormones (TH) and glucocorticoids (GC) are involved in numerous developmental and physiological processes. The effects… Frontiers in Genetics vol. 23, n° 22, p. 13715
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, October 2022Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system. Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances and a major pollutant in households and… International Journal of Molecular Sciences vol. 13, , p. 996826
  • Nguyen Duy, Buisine Nicolas, Fayol Olivier, Michels Annemieke A., Bensaude Olivier, Price David H. & Uguen Patricia, August 2021An alternative D. melanogaster 7SK snRNP. BACKGROUND: The 7SK small nuclear RNA (snRNA) found in most metazoans is a key regulator of P-TEFb which in turn regulates RNA… BMC Mol Cell Biol vol. 22, n° 1, p. 43
  • Thambirajah Anita A., Wade Michael G., Verreault Jonathan, Buisine Nicolas, Alves Verônica A., Langlois Valerie S. & Helbing Caren C., August 2021Disruption by stealth - Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals. Thyroid hormones (THs) are important regulators of growth, development, and homeostasis of all vertebrates. There are many… Environ Res vol. 203, , p. 111906
  • Tribondeau Alicia, Sachs Laurent M. & Buisine Nicolas, June 2021Are paedomorphs actual larvae?. Amphibians display very diverse life cycles and development can be direct, where it occurs in ovo and a juvenile hatches… Dev Dyn vol. 250, n° 6, p. 779-787
  • Antoine-Lorquin Aymeric, Arensburger Peter, Arnaoty Ahmed, Asgari Sassan, Batailler Martine, Beauclair Linda, Belleannée Catherine, Buisine Nicolas, Coustham Vincent, Guyetant Serge, Helou Laura, Lecomte Thierry, Pitard Bruno, Stévant Isabelle & Bigot Yves, May 2021Two repeated motifs enriched within some enhancers and origins of replication are bound by SETMAR isoforms in human colon cells. Setmar is a gene specific to simian genomes. The function(s) of its isoforms are poorly understood and their existence in… Genomics vol. 113, n° 3, p. 1589-1604
  • Helou Laura, Beauclair Linda, Dardente Hugues, Arensburger Peter, Buisine Nicolas, Jaszczyszyn Yan, Guillou Florian, Lecomte Thierry, Kentsis Alex & Bigot Yves, April 2021The C-terminal Domain of piggyBac Transposase Is Not Required for DNA Transposition. PiggyBac(PB)-like elements (pble) are members of a eukaryotic DNA transposon family. This family is of interest to evolutionary… J Mol Biol vol. 433, n° 7, p. 166805
  • Buisine Nicolas, Grimaldi Alexis, Jonchere Vincent, Rigolet Muriel, Blugeon Corinne, Hamroune Juliette & Sachs Laurent M, 2021Transcriptome and Methylome Analysis Reveal Complex Cross-Talks between Thyroid Hormone and Glucocorticoid Signaling at Xenopus Metamorphosis. Background: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two… Cells vol. 10, n° 9, p. 2375